4bnz A 2.5 BS01 8M5 A 1 F107 V110 L114 A156 G160 F164 F101 V104 L108 A150 G154 F158 G16 S141 Y154 K158 G18 S135 Y148 K152 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.26uM -logKd/Ki=6.59, IC50=0.26uM O54438 24015914 1248 QSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bnz B 2.5 BS01 8M5 A 1 V110 L114 G163 V108 L112 G156 G16 S141 Y154 K158 G22 S139 Y147 K151 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 -logKd/Ki=6.59, IC50=0.26uM O54438 24015914 1248 NLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITRDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bnz C 2.5 BS01 8M5 D 1 V110 L114 A156 G163 F164 V111 L115 A157 G164 F165 G16 S141 Y154 K158 G29 S142 Y155 K159 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 O54438 24015914 1248 HHHHHSSNLYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS 4bnz D 2.5 BS01 8M5 D 1 W106 V110 L114 G160 G163 F164 W106 V110 L114 G160 G163 F164 G16 S141 Y154 K158 G21 S141 Y154 K158 1.1.1.100 0004316,0006633,0016491,0016616,0030497,0050661,0051287 ic50=0.26uM O54438 24015914 1248 LYFQSMSLQGKVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLKANGVEGAGLVLDVSSDESVAATLEHIQQHLGQPLIVVNNAGITVRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKARWGRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFIDTDMTRELPEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGAAYVTGATVPVNGGMYMS