3b8r A 2.7 BS01 887 A 1 L840 V848 A866 K868 E885 L889 T916 C919 L1035 C1045 D1046 F1047 L23 V26 A44 K46 E63 L67 T94 C97 L163 C173 D174 F175 D1028 A1030 R1032 N1033 D1046 D156 A158 R160 N161 D174 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 -logKd/Ki=9.22, IC50=0.6nM IC50=0.600000nM P35968 18324759 201 ERLPYDASKWEFPRDRLKLGKPLGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH 3b8r B 2.7 BS01 887 B 1 L840 A866 K868 E885 L889 T916 C919 L1035 C1045 D1046 F1047 L20 A43 K45 E59 L63 T90 C93 L153 C163 D164 F165 D1028 A1030 R1032 N1033 D1046 D146 A148 R150 N151 D164 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 IC50=0.600000nM P35968 18324759 202 PYDASKWEFPRDRLKLGKPLGRGQVIEADAFGIDKTATCRTVAVKMLATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVITEFCKFGNLSTYLRSKRNEFVPYKYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQA