5x26 A 2.951 BS01 7XO A 1 L718 A743 K745 M766 T790 M793 P794 G796 L844 L22 A47 K49 M70 T94 M97 P98 G100 L148 D837 A839 R841 N842 D855 D141 A143 R145 N146 D159 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=8.30, IC50=5nM IC50=5nM P00533 29568384 1101 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLGAEEVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPEEDMDDVVDADEYLIPQ 5x2a A 1.85 BS01 7XO A 1 V726 A743 K745 M790 M793 P794 G796 D855 V27 A44 K46 M91 M94 P95 G97 D156 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1107 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMVV 5x2a B 1.85 BS01 7XO B 1 M793 P794 G796 M94 P95 G97 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1105 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQG 5x2a C 1.85 BS01 7XO C 1 V726 A743 K745 M790 M793 G796 L844 D855 V27 A44 K46 M91 M94 G97 L145 D156 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 IC50=5nM P00533 29568384 1104 NQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMRKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADE