5tx5 A 2.56 BS01 7MJ A 1 V31 K45 M67 V76 L90 M92 H136 A155 D156 L157 L159 F162 V20 K34 M56 V65 L79 M81 H125 A144 D145 L146 L148 F151 D138 K140 E142 N143 D156 T189 D127 K129 E131 N132 D145 T160 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.80, IC50=0.016uM Q13546 28151659 301 IKMKSSDFLESAELDSGGKVSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE 5tx5 B 2.56 BS01 7MJ B 1 M44 K45 V76 L90 M92 H136 A155 D156 L157 M25 K26 V57 L71 M73 H117 A136 D137 L138 D138 K140 E142 N143 D156 T189 D119 K121 E123 N124 D137 T158 2.7.11.1 0004672,0005524,0006468 Q13546 28151659 301 VIKMKSSDFLESSLAFHRTQGLMIMKTVYKGPNCIEHNEALLEEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRIILEIIEGMAYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAIAEQQLIMAIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQLE