5tuy A 2.6 BS06 7L6 A 1 D1074 A1077 D1078 R1080 D1083 L1086 D1088 R1157 F1158 D154 A157 D158 R160 D163 L166 D168 R237 F238 Y1067 Y1154 Y147 Y234 2.1.1.-,2.1.1.367 0002039,0005634,0008270,0016279,0042054 -logKd/Ki=6.35, Kd=445nM IC50=1.6nM, Kd=445nM Q96KQ7 28135087 1506 IICRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDNKDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQS 5tuy B 2.6 BS06 7L6 B 1 A1077 D1078 D1083 L1086 D1088 F1158 I1161 K1162 A155 D156 D161 L164 D166 F233 I236 K237 Y1067 Y1154 Y145 Y229 2.1.1.-,2.1.1.367 0002039,0005634,0008270,0016279,0042054 IC50=1.6nM, Kd=445nM Q96KQ7 28135087 1506 CRDVARGYENVPIPCVNGVDGEPCPEDYKYISENCETSTMNIDRNITHLQHCTCVDDCSSSNCLCGQLSIRCWYDKDGRLLQEFNKIEPPLIFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAKMGWGVRALQTIPQGTFICEYVGELISDAEADVREDDSYLFDLDGEVYCIDARYYGNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDIKSKYFTCQCGSEKCKHSAEAIALEQSK 5tuz A 1.95 BS06 7L6 A 1 A1165 D1166 R1168 D1171 L1174 D1176 R1245 F1246 I1249 A160 D161 R163 D166 L169 D171 R238 F239 I242 Y1155 Y1242 Y150 Y235 2.1.1.-,2.1.1.367 0002039,0005634,0008270,0016279,0042054 Kd=40nM -logKd/Ki=7.40, Kd=40nM IC50=13nM, Kd=40nM Q9H9B1 28135087 3006 VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDNGEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS 5tuz B 1.95 BS06 7L6 B 1 D1162 A1165 D1166 D1171 L1174 D1176 R1245 F1246 I1249 K1250 D157 A160 D161 D166 L169 D171 R236 F237 I240 K241 Y1155 Y1242 Y150 Y233 2.1.1.-,2.1.1.367 0002039,0005634,0008270,0016279,0042054 Kd=40nM IC50=13nM, Kd=40nM Q9H9B1 28135087 3006 VERIVSRDIARGYERIPIPCVNAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDCSSSNCMCGQLSMRCWYDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRDMGWGVRSLQDIPPGTFVCEYVGELISDSEADVREEDSYLFDLDEVYCIDARFYGNVSRFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDIKGKLFSCRCGSPKCRHS