5k6a A 1.7 BS02 6QT A 1 S95 F97 Y174 V206 P210 W221 S94 F96 Y154 V186 P190 W201 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM -logKd/Ki=4.51, IC50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a B 1.7 BS02 6QT B 1 F97 Y174 W221 F96 Y153 W200 R14 D161 Y174 K178 R13 D140 Y153 K157 ? 0000166,0016491,0047040 ic50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a C 1.7 BS02 6QT C 1 F97 Y174 V206 W221 F96 Y154 V186 W191 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5k6a D 1.7 BS02 6QT D 1 S95 F97 Y174 V206 P210 W221 S94 F96 Y154 V186 P190 W201 R14 D161 Y174 K178 R13 D141 Y154 K158 ? 0000166,0016491,0047040 ic50=31uM -logKd/Ki=4.51, IC50=31uM O76290 28282886 302 EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVKTVETQVAELIGTNAIAPFLLTMSFAQRQSNLSIVNLCDAMVDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA 5l4n A 2.35 BS01 6QT A 1 S111 F113 Y194 L226 S100 F102 Y169 L201 R17 D181 Y194 R13 D156 Y169 1.5.1.33 0004155,0005829,0006729,0016491,0031427,0047040 ic50=57uM Q01782 28282886 601 TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA 5l4n B 2.35 BS01 6QT B 1 S111 F113 Y194 L226 S100 F102 Y170 L202 R17 D181 Y194 R13 D157 Y170 1.5.1.33 0004155,0005829,0006729,0016491,0031427,0047040 ic50=57uM Q01782 28282886 601 TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA