5hvu A 2.8 BS01 65R A 1 F87 G88 E89 V90 A103 K105 D117 F120 M156 A215 D216 F82 G83 E84 V85 A98 K100 D112 F115 M151 A210 D211 D198 K200 N203 D216 T237 D193 K195 N198 D211 T232 2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=7.89, Ki=13nM Ki=13nM, IC50=7.0nM Q13464 29945794 501 SFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEETFPIPKAFVGNQLPFVGFTYYSNRRY 5hvu B 2.8 BS01 65R B 1 I82 F87 G88 V90 A103 K105 D117 F120 Y155 M156 A215 D216 I78 F83 G84 V86 A99 K101 D113 F116 Y151 M152 A211 D212 D198 K200 N203 D216 T237 D194 K196 N199 D212 T229 2.7.11.1 0004672,0004674,0005524,0006468 Ki=13nM, IC50=7.0nM Q13464 29945794 501 MSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSN