2p2i A 2.4 BS01 608 A 1 L840 A866 K868 E885 I892 V916 C919 C1024 H1026 L1035 C1045 D1046 F1047 L24 A47 K49 E62 I69 V93 C96 C151 H153 L162 C172 D173 F174 D1028 A1030 R1032 N1033 D1046 D155 A157 R159 N160 D173 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 ic50=38nM -logKd/Ki=7.42, IC50=38nM IC50=38nM, Ki=10nM P35968 17253678 501 AERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDTCRTVAVKMLTHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKVAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLALPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDRHHHHHH 2p2i B 2.4 BS01 608 B 1 L840 A866 K868 E885 V916 F918 C1024 I1025 H1026 L1035 C1045 D1046 F1047 L21 A44 K46 E59 V90 F92 C139 I140 H141 L150 C160 D161 F162 D1028 A1030 R1032 N1033 D1046 D143 A145 R147 N148 D161 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169 ic50=38nM IC50=38nM, Ki=10nM P35968 17253678 502 LPYDASKWEFPRDRLKLGKPLGRGQVIEADAFGIDKTATCRTVAVKMLTHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRSKRNEFVPYKFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANA