1mrs A 2.0 BS02 5HU A 1 D9 P37 Y39 F70 R74 R95 N100 Y103 Y165 D9 P37 Y39 F70 R74 R95 N100 Y103 Y165 2.7.4.9 0000287,0004798,0005524,0005525,0005737,0005829,0006227,0006233,0006235,0009165,0016301,0016310,0042803,0046044,0046872,0046940 Ki=110uM -logKd/Ki=3.96, Ki=110uM P9WKE1 12454011 217 MLIAIEGVDGAGKRTLVEKLSGAFRAAGRSVATLAFPRYGQSVAADIAAEALHGEHGDLASSVYAMATLFALDRAGAVHTIQGLCRGYDVVILDRYVASNAAYSAARLHENAAGKAAAWVQRIEFARLGLPKPDWQVLLAVSAELAGERSRGRAQRDPGRARDNYERDAELQQRTGAVYAELAAQGWGGRWLVVGADVDPGRLAATLA 7jxf A 1.5 BS01 5HU A 1 R21 W80 Y94 C146 H147 Q165 R166 S167 D169 N177 H207 Y209 R21 W80 Y94 C146 H147 Q165 R166 S167 D169 N177 H207 Y209 E58 W80 Y94 C146 R166 D169 E58 W80 Y94 C146 R166 D169 2.1.1.45 0000287,0003723,0004799,0005737,0005829,0006231,0006235,0006417,0008168,0009165,0009314,0016741,0032259,0042803 P0A884 33829766 301 MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 7jxf B 1.5 BS01 5HU A 1 R126 R127 R126 R127 E58 W80 Y94 C146 R166 D169 E58 W80 Y94 C146 R166 D169 2.1.1.45 0000287,0003723,0004799,0005737,0005829,0006231,0006235,0006417,0008168,0009165,0009314,0016741,0032259,0042803 P0A884 33829766 301 MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI 8qhq A 1.78 BS01 5HU A 1 C26 G27 S28 I29 R30 H56 I76 S98 G100 Q104 C9 G10 S11 I12 R13 H39 I57 S79 G81 Q85 3.2.2.- 0009159,0070694 O43598 37884503 201 MGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADP 8qhq A 1.78 BS02 5HU B 1 S128 A129 M130 S109 A110 M111 3.2.2.- 0009159,0070694 O43598 37884503 201 MGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADP 8qhq B 1.78 BS01 5HU A 1 S128 A129 M130 S110 A111 M112 3.2.2.- 0009159,0070694 O43598 37884503 201 GRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEAD 8qhq B 1.78 BS02 5HU B 1 C26 G27 S28 I29 R30 H56 I76 S98 G100 Q104 C8 G9 S10 I11 R12 H38 I58 S80 G82 Q86 3.2.2.- 0009159,0070694 O43598 37884503 201 GRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEAD 8qhq C 1.78 BS01 5HU C 1 C26 G27 S28 I29 R30 I76 S98 G100 Q104 C9 G10 S11 I12 R13 I57 S79 G81 Q85 3.2.2.- 0009159,0070694 O43598 37884503 201 MGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADP 8qhq C 1.78 BS02 5HU D 1 S128 A129 M130 S109 A110 M111 3.2.2.- 0009159,0070694 O43598 37884503 201 MGRPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEADP 8qhq D 1.78 BS01 5HU C 1 S128 A129 M130 S109 A110 M111 3.2.2.- 0009159,0070694 O43598 37884503 201 RPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFE 8qhq D 1.78 BS02 5HU D 1 C26 G27 S28 I29 R30 H56 I76 S98 G100 Q104 C7 G8 S9 I10 R11 H37 I57 S79 G81 Q85 3.2.2.- 0009159,0070694 O43598 37884503 201 RPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAELGARGEEAAGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFE 8qhq E 1.78 BS01 5HU E 1 C26 G27 S28 I29 R30 H56 V57 I76 S98 G100 Q104 C7 G8 S9 I10 R11 H37 V38 I48 S70 G72 Q76 3.2.2.- 0009159,0070694 O43598 37884503 201 RPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAEGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEA 8qhq F 1.78 BS01 5HU F 1 C26 G27 S28 I29 R30 H56 V57 I76 S98 G100 Q104 C7 G8 S9 I10 R11 H37 V38 I48 S70 G72 Q76 3.2.2.- 0009159,0070694 O43598 37884503 201 RPALYFCGSIRGGREDRTLYERIVSRLRRFGTVLTEHVAAAEGGDRLIHEQDLEWLQQADVVVAEVTQPSLGVGYQLGRAVAFNKRILCLFRPQSGRVLSAMIRGAADGSRFQVWDYEEGEVEALLDRYFEA