5gso A 2.6 BS01 5GI A 1 H40 E71 K130 T142 K143 C147 H161 I162 G163 G164 H40 E71 K130 T142 K143 C147 H161 I162 G163 G164 V30 H40 E71 G145 C147 V30 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 -logKd/Ki=6.96, IC50=0.11uM E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gso B 2.6 BS01 5GI B 1 R39 H40 E71 S128 T142 K143 C147 H161 I162 G163 G164 R39 H40 E71 S128 T142 K143 C147 H161 I162 G163 G164 V30 H40 E71 G145 C147 V30 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gso C 2.6 BS01 5GI C 1 H40 L127 K130 T142 K143 C147 H161 I162 G163 G164 H40 L127 K130 T142 K143 C147 H161 I162 G163 G164 V30 H40 E71 G145 C147 V30 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gso D 2.6 BS01 5GI D 1 H40 E71 L127 S128 T142 K143 A144 C147 H161 I162 G163 G164 H38 E69 L125 S126 T140 K141 A142 C145 H159 I160 G161 G162 V30 H40 E71 G145 C147 V28 H38 E69 G143 C145 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 SLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gso E 2.6 BS01 5GI E 1 H40 E71 L127 T142 K143 C147 H161 I162 G163 G164 H40 E71 L127 T142 K143 C147 H161 I162 G163 G164 V30 H40 E71 G145 C147 V30 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVNLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gsw A 3.19 BS01 5GI A 1 H40 E71 S128 K130 T142 K143 C147 H161 I162 G163 G164 H40 E71 S128 K130 T142 K143 C147 H161 I162 G163 G164 H40 E71 G145 C147 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 -logKd/Ki=5.94, IC50=1.15uM E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVSLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gsw B 3.19 BS01 5GI B 1 H40 E71 L127 T142 K143 C147 H161 I162 G163 G164 H39 E70 L126 T141 K142 C146 H160 I161 G162 G163 H40 E71 G145 C147 H39 E70 G144 C146 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 PSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVSLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gsw C 3.19 BS01 5GI C 1 R39 H40 E71 L127 S128 T142 K143 A144 C147 H161 I162 G163 G164 R39 H40 E71 L127 S128 T142 K143 A144 C147 H161 I162 G163 G164 H40 E71 G145 C147 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVSLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gsw D 3.19 BS01 5GI D 1 H40 E71 L127 T142 C147 H161 I162 G163 G164 H40 E71 L127 T142 C147 H161 I162 G163 G164 H40 E71 G145 C147 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVSLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS 5gsw E 3.19 BS01 5GI E 1 R39 H40 E71 T142 K143 C147 H161 I162 G163 G164 R39 H40 E71 T142 K143 C147 H161 I162 G163 G164 H40 E71 G145 C147 H40 E71 G145 C147 ? 0004197,0005737,0006508,0008234,0018144,0019062,0030430,0039618,0046718 E7E815 28461310 201 GPSLDFALSLLRRNVRQVQTDQGHFTMLGVRDRLAVLPRHSQPGKTIWIEHKLVNVLDAVELVDEQGVSLELTLITLDTNEKFRDITKFIPENISTASDATLVINTEHMPSMFVPVGDVVQYGFLNLSGKPTHRTMMYNFPTKAGQCGGVVTSVGKIIGIHIGGNGRQGFCAGLKRSYFAS