1rwq A 2.2 BS01 5AP A 1 R125 E205 E206 Y547 S630 Y662 Y666 R87 E167 E168 Y509 S592 Y624 Y628 Y547 S630 Y631 D708 H740 Y509 S592 Y593 D670 H702 3.4.14.5 0001618,0001662,0001666,0002020,0004177,0004252,0005102,0005515,0005576,0005765,0005886,0005925,0006508,0007155,0008236,0008239,0008284,0009986,0010716,0016020,0016324,0016486,0019065,0030027,0030139,0031258,0031295,0033632,0035641,0036343,0042110,0042802,0042803,0042995,0043542,0045121,0045499,0046581,0046718,0046813,0050919,0061025,0070062,0070161,0090024,0120116 ic50=0.0001uM -logKd/Ki=10.00, IC50=0.1nM IC50=0.1nM P27487 15006388 900 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 1rwq B 2.2 BS01 5AP B 1 R125 E205 E206 Y547 S630 Y631 Y662 Y666 N710 R87 E167 E168 Y509 S592 Y593 Y624 Y628 N672 Y547 S630 Y631 D708 H740 Y509 S592 Y593 D670 H702 3.4.14.5 0001618,0001662,0001666,0002020,0004177,0004252,0005102,0005515,0005576,0005765,0005886,0005925,0006508,0007155,0008236,0008239,0008284,0009986,0010716,0016020,0016324,0016486,0019065,0030027,0030139,0031258,0031295,0033632,0035641,0036343,0042110,0042802,0042803,0042995,0043542,0045121,0045499,0046581,0046718,0046813,0050919,0061025,0070062,0070161,0090024,0120116 ic50=0.0001uM IC50=0.1nM P27487 15006388 1900 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP