5csp A 1.5 BS01 54G A 1 V53 K68 F113 I174 D175 V51 K66 F111 I172 D173 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 Kd=58uM -logKd/Ki=4.24, Kd=58uM Kd=58000nM P68400 28451126 401 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5cu0 A 2.18 BS03 54G A 1 V53 V66 K68 F113 M163 I174 D175 V52 V65 K67 F112 M162 I173 D174 D156 K158 N161 D175 P184 S194 D155 K157 N160 D174 P183 S193 2.7.11.1 0004672,0004674,0005524,0006468 Kd=58000nM P68400 28495381 403 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5cu0 B 2.18 BS03 54G B 1 V66 K68 F113 M163 I174 D175 V63 K65 F110 M160 I171 D172 D156 K158 N161 D175 P184 S194 D153 K155 N158 D172 P181 S191 2.7.11.1 0004672,0004674,0005524,0006468 Kd=58000nM P68400 28495381 403 PVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVV 5cu2 A 1.705 BS04 54G A 1 V53 V66 K68 F113 M163 I174 D175 V52 V65 K67 F112 M162 I173 D174 D156 K158 N161 D175 P184 S194 D155 K157 N160 D174 P183 S193 2.7.11.1 0004672,0004674,0005524,0006468 -logKd/Ki=4.24, Kd=58uM Kd=58000nM P68400 28495381 404 SGPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 5cu2 B 1.705 BS03 54G B 1 K68 F113 M163 I174 D175 K66 F111 M161 I172 D173 D156 K158 N161 D175 P184 S194 D154 K156 N159 D173 P182 S192 2.7.11.1 0004672,0004674,0005524,0006468 Kd=58000nM P68400 28495381 403 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVKKKKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTV 5rt9 A 1.01 BS01 54G A 1 G48 V49 F156 G46 V47 F154 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- P0DTD1 33853786 201 VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL 6ehk A 1.4 BS02 54G A 1 V53 V66 K68 F113 M163 I174 D175 V51 V64 K66 F111 M161 I172 D173 D156 K158 N161 D175 S194 D154 K156 N159 D173 S192 2.7.11.1 0004672,0004674,0005524,0006468 Kd=58000nM P68400 29732088 404 GPVPSRARVYTDVNTHRPSEYWDYESHVVEWGNQDDYQLVRKLGRGKYSEVFEAINITNNEKVVVKILKPVAAAKIKREIKILENLRGGPNIITLADIVKDPVSRTPALVFEHVNNTDFKQLYQTLTDYDIRFYMYEILKALDYCHSMGIMHRDVKPHNVMIDHEHRKLRLIDWGLAEFYHPGQEYNVRVASRYFKGPELLVDYQMYDYSLDMWSLGCMLASMIFRKEPFFHGHDNYDQLVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWERFVHSENQHLVSPEALDFLDKLLRYDHQSRLTAREAMEHPYFYTVVK 7zt7 A 1.84 BS01 54G A 1 Y7 R9 S24 K43 W69 Y8 R10 S25 K44 W70 ? Q95460 37382893 301 MRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGCELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNEIVQEIDYGDILPSGDGTYQAWASIELDPSNLYSCHVEHSGVHMVLQVP