5cas A 2.1 BS01 4ZQ A 1 L718 G719 V726 A743 K745 E762 M766 C775 M790 Q791 M793 L844 T854 L23 G24 V31 A48 K50 E63 M67 C76 M91 Q92 M94 L145 T155 D837 A839 R841 N842 D855 D138 A140 R142 N143 D156 2.7.10.1 0004672,0004713,0005524,0006468 Ki=1.4nM -logKd/Ki=8.85, Ki=1.4nM P00533 26455919 1102 GEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLIMQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGRAKLLVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYMDDVVDADEYLIP 5cav A 2.73 BS01 4ZQ A 1 L718 V726 A743 K745 C775 T790 Q791 L792 M793 G796 L844 T854 D855 L22 V30 A47 K49 C79 T94 Q95 L96 M97 G100 L148 T158 D159 D837 A839 R841 N842 D855 G874 D141 A143 R145 N146 D159 G178 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=6.67, Ki=216nM P00533 26455919 1101 EAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDDEEDMDDVVDADEYLIPQ