5c4s A 2.23 BS01 4Y5 A 1 L324 T325 I328 Q329 M358 V480 L483 Q484 Q487 A496 A497 F498 L501 L505 F506 L58 T59 I62 Q63 M92 V214 L217 Q218 Q221 A230 A231 F232 L235 L239 F240 ? 0003677,0004879,0005634,0006355 ic50=3.8nM -logKd/Ki=8.42, IC50=3.8nM IC50=3.8nM P51449 26640126 601 LTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLHKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fav A 1.85 BS02 4Y5 A 1 L324 T325 I328 Q329 M358 L483 Q484 Q487 A496 A497 F498 L501 Y502 L505 F506 L65 T66 I69 Q70 M99 L224 Q225 Q228 A237 A238 F239 L242 Y243 L246 F247 ? 0003677,0004879,0005634,0006355 P51449 36793423 602 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fav B 1.85 BS02 4Y5 B 1 L324 T325 I328 Q329 K354 M358 L483 Q484 Q487 A496 A497 F498 L501 Y502 L505 F506 L65 T66 I69 Q70 K95 M99 L224 Q225 Q228 A237 A238 F239 L242 Y243 L246 F247 ? 0003677,0004879,0005634,0006355 P51449 36793423 602 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fb1 A 2.18 BS02 4Y5 A 1 L324 T325 I328 Q329 M358 L483 Q484 Q487 A496 A497 F498 L501 Y502 L505 F506 L65 T66 I69 Q70 M99 L224 Q225 Q228 A237 A238 F239 L242 Y243 L246 F247 ? 0003677,0004879,0005634,0006355 P51449 36793423 602 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fb1 A 2.18 BS03 4Y5 A 2 L267 E271 H452 C455 K456 L8 E12 H193 C196 K197 ? 0003677,0004879,0005634,0006355 P51449 36793423 603 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fb1 B 2.18 BS01 4Y5 A 2 H451 Q460 L463 A464 H192 Q201 L204 A205 ? 0003677,0004879,0005634,0006355 P51449 36793423 603 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS 8fb1 B 2.18 BS03 4Y5 B 1 L324 T325 I328 Q329 K354 M358 L483 Q484 Q487 A496 A497 F498 L501 Y502 L505 F506 L65 T66 I69 Q70 K95 M99 L224 Q225 Q228 A237 A238 F239 L242 Y243 L246 F247 ? 0003677,0004879,0005634,0006355 P51449 36793423 602 PEAPYASLTEIEHLVQSVSKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELSQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCSELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHRQSILAKLPPKGKLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFS