1xka C 2.3 BS02 4PP C 1 T98 Y99 F174 D189 A190 Q192 S195 V213 W215 G216 G218 T84 Y85 F162 D179 A180 Q182 S185 V203 W205 G206 G208 G193 S195 G196 G183 S185 G186 3.4.21.6 0004252,0006508 Ki=131nM -logKd/Ki=6.88, Ki=131nM IC50=270nM P00742 9618463 500 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTR 1xkb C 2.4 BS02 4PP C 1 T98 Y99 F174 D189 A190 C191 Q192 S195 V213 W215 G216 G218 T84 Y85 F162 D179 A180 C181 Q182 S185 V203 W205 G206 G208 E86 T132 G193 S195 G196 E72 T121 G183 S185 G186 3.4.21.6 0004252,0006508 Ki=131nM IC50=270nM P00742 9618463 998 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKTR 1xkb D 2.4 BS02 4PP D 1 T98 Y99 F174 D189 A190 C191 Q192 S195 V213 W215 G216 G218 T84 Y85 F162 D179 A180 C181 Q182 S185 V203 W205 G206 G208 H57 D102 Q192 G193 D194 S195 G196 H42 D88 Q182 G183 D184 S185 G186 3.4.21.6 0004252,0006508 Ki=131nM IC50=270nM P00742 9618463 999 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTEQEEGGEAVHEVEVVIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPERDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWIDRSMKT