1gjp A 1.8 BS01 4OX A 1 S179 Y207 K210 F219 K263 Y287 S290 Y329 S179 Y207 K210 F219 K263 Y287 S290 Y329 K210 K263 K210 K263 4.2.1.24 0004655,0005634,0005737,0005829,0006782,0006783,0008270,0016829,0033014,0046872 P05373 11513881 363 MHTAEFLETEPTEISSVLAGGYNHPLLRQWQSERQLTKNMLIFPLFISDNPDDFTEIDSLPNINRIGVNRLKDYLKPLVAKGLRSVILFGVPLIPGTKDPVGTAADDPAGPVIQGIKFIREYFPELYIICDVCLCEYTSHGHCGVLYDDGTINRERSVSRLAAVAVNYAKAGAHCVAPSDMIDGRIRDIKRGLINANLAHKTFVLSYAAKFSGNLYGPFRDAACSAPSNGDRKCYQLPPAGRGLARRALERDMSEGADGIIVKPSTFYLDIMRDASEICKDLPICAYHVSGEYAMLHAAAEKGVVDLKTIAFESHQGFLRAGARLIITYLAPEFLDWLDE 1l6y A 1.9 BS02 4OX A 1 K194 Y200 F203 R204 R215 Q219 K246 V271 S272 Y311 K194 Y200 F203 R204 R215 Q219 K246 V271 S272 Y311 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 -logKd/Ki=3.66, IC50=0.22mM P0ACB2 11909869 350 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR 1l6y B 1.9 BS02 4OX B 1 K194 F203 R204 R215 K246 Y269 V271 S272 Y311 K194 F203 R204 R215 K246 Y269 V271 S272 Y311 K194 K246 K194 K246 4.2.1.24 0000287,0004655,0005829,0006782,0006783,0008270,0016829,0033014,0046872 P0ACB2 11909869 350 TDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDYKAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARMSRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGADFIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKSYQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR