4ybk A 2.5 BS01 4B7 A 1 L273 A293 K295 M314 I336 T338 Y340 M341 S342 G344 L393 D404 F405 L18 A38 K40 M59 I81 T83 Y85 M86 S87 G89 L138 D149 F150 D386 R388 A390 N391 D404 F424 D131 R133 A135 N136 D149 F157 2.7.10.2 0004672,0004713,0005524,0006468 Kd=15nM -logKd/Ki=7.82, Kd=15nM P00523 26895387 601 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 4yc8 A 2.9 BS01 4B7 A 1 L248 A269 K271 F283 A287 M290 I313 T315 M318 T319 Y320 G321 L370 F382 L16 A31 K33 F41 A45 M48 I71 T73 M76 T77 Y78 G79 L128 F140 D363 A365 R367 N368 D381 P402 D121 A123 R125 N126 D139 P160 2.7.10.2 0004672,0004713,0005524,0006468 -logKd/Ki=7.85, Kd=14nM P00519 26895387 601 DKWEMERTDITMKHKLEVYEGVWKKYSLTVAVKTLMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESS 4yc8 B 2.9 BS01 4B7 B 1 A269 K271 M290 I313 T315 F317 M318 T319 G321 F382 A31 K33 M52 I75 T77 F79 M80 T81 G83 F144 D363 A365 R367 N368 D381 P402 D125 A127 R129 N130 D143 P164 2.7.10.2 0004672,0004713,0005524,0006468 P00519 26895387 601 DKWEMERTDITMKHKLEVYEGVWKKYSLTVAVKTLKEDTMEVEEFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSI