4wnk A 2.42 BS01 453 A 1 G193 K194 G195 F197 G198 V200 A213 K215 M230 I265 M266 E315 N316 L318 D329 G170 K171 G172 F174 G175 V177 A190 K192 M207 I242 M243 E292 N293 L295 D306 D311 K313 E315 N316 D329 E338 T348 D288 K290 E292 N293 D306 E315 T325 2.7.11.16 0004672,0004674,0004703,0005524,0005634,0005737,0005886,0006468,0006915,0007165,0008289,0009966,0016055,0016310,0043066,0046777 ic50=0.38uM -logKd/Ki=6.42, IC50=0.38uM P43249 26032411 701 KGKSKKWKEILKFPHINQCEDLRRTIDRDYCSLCDKQPVGRLLFRQFCETRPGLESYIQFLDSVAEYEVTPDEKLGEKGKEIMTKYLTPKSPVFITQVGRDLVSQTEEKLLQKPCKELFSACVQSVHDYLRGEPFHEYLDSMYFDRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKRLEKKRIKKRKGESMALNEKQILEKVNSRFVVNLAYAYETKDALCLVLTIMNGGDLKFHIYNMGNPGFEEERALFYAAEILCGLEDLHHENIVYRDLKPENILLDDYGHIRISDLGLAVKIPEGDLIRGRVGTVGYMAPEVLNNQRYGLSPDYWGLGCLIYEMIEGQSPFRGRKEKVKREEVDRRVLETEEVYSHKFSEEAKSICKMLLTKDAKQRLGCQEEGAAEVKRHPFFRNMNFKRLEAGMLDPPFVPDPRAVYHTDDDFYSKFSTGSVPIPWQSEMIETECFKELNVFGPHGTLSPDLNRSH 5he0 A 2.56 BS01 453 A 1 I197 G198 R199 G200 G201 F202 G203 V205 A218 L235 M274 L324 S334 D335 I168 G169 R170 G171 G172 F173 G174 V176 A189 L206 M245 L295 S305 D306 D317 K319 N322 D335 K344 T353 D288 K290 N293 D306 K315 T324 2.7.11.15 0001664,0002026,0002029,0002031,0003108,0004672,0004674,0004703,0005515,0005524,0005737,0005829,0005886,0006468,0006886,0007165,0007186,0007213,0009966,0016020,0016310,0018105,0031694,0031755,0042995,0045202,0045880,0045988,0047696,0060048,0098793,0098794,1901081,1903566 -logKd/Ki=6.82, IC50=0.15uM P21146 27050625 701 KKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLKHLEEAKPLVEFYEEIKKYEKLETEEERLVCSREIFDTYIMKELLACSHPFSKSAIEHVQGHLVKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGDCPFIVCMSYAFHTPDKLSFILDLMNGGDLHYHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLDEHGHVRISDLGLACDFSKKKPHASVGTHGYMAPEVLQKGVAYDSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMTLTMAVELPDSFSPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFFRSLDWQMVFLQKYPPPLIPPRGKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDTINAETDRLEARKKTKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGEGEAPQSLLTMEEIQSVEETQIKERKCLLLKIRGGKQFVLQCDSDPELVQWKKELRDAYREAQQLVQRVPKMKNKP