3ig6 B 1.83 BS02 438 B 1 V41 C42 H57 L97B A98 H99 D189 S190 C191 Q192 G193 S195 V213 W215 G216 G218 V30 C31 H46 L92 A93 H94 D192 S193 C194 Q195 G196 S198 V216 W218 G219 G221 H57 D102 Q192 G193 D194 S195 G196 H46 D97 Q195 G196 D197 S198 G199 3.4.21.73 0004252,0006508 ic50=0.025uM -logKd/Ki=7.60, IC50=0.025uM IC50=25nM P00749 19703768 400 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHT 3ig6 B 1.83 BS03 438 D 1 Y149 L150 Y148 L149 H57 D102 Q192 G193 D194 S195 G196 H46 D97 Q195 G196 D197 S198 G199 3.4.21.73 0004252,0006508 ic50=0.025uM -logKd/Ki=7.60, IC50=0.025uM IC50=25nM P00749 19703768 401 IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHT 3ig6 D 1.83 BS02 438 B 1 I60 K92 Y94 S95 A96 I46 K82 Y84 S85 A86 H57 D102 Q192 G193 D194 S195 G196 H43 D94 Q192 G193 D194 S195 G196 3.4.21.73 0004252,0006508 ic50=0.025uM IC50=25nM P00749 19703768 400 IIGGEFTTIENQPWFAAIYRRHSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 3ig6 D 1.83 BS03 438 D 1 K143 D189 S190 C191 Q192 W215 G216 R217 G218 K139 D189 S190 C191 Q192 W215 G216 R217 G218 H57 D102 Q192 G193 D194 S195 G196 H43 D94 Q192 G193 D194 S195 G196 3.4.21.73 0004252,0006508 ic50=0.025uM IC50=25nM P00749 19703768 401 IIGGEFTTIENQPWFAAIYRRHSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK