4rz1 A 2.6 BS01 3ZN A 1 T12 Q13 V30 D32 G34 Y75 S76 T77 P111 L114 F117 L213 D215 G217 A218 I291 T17 Q18 V35 D37 G39 Y82 S83 T84 P117 L120 F123 L220 D222 G224 A225 I301 D32 S35 N37 W39 Y75 D215 A218 D37 S40 N42 W44 Y82 D222 A225 3.4.23.15 0004190,0006508 -logKd/Ki=7.40, IC50=0.04uM IC50=80nM P00797 25754490 1001 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR 4rz1 B 2.6 BS01 3ZN B 1 T12 Q13 V30 D32 G34 Y75 S76 T77 P111 L114 F117 L213 D215 G217 A218 I291 T295 T17 Q18 V35 D37 G39 Y82 S83 T84 P117 L120 F123 L220 D222 G224 A225 I301 T305 D32 S35 N37 W39 Y75 D215 A218 D37 S40 N42 W44 Y82 D222 A225 3.4.23.15 0004190,0006508 IC50=80nM P00797 25754490 1001 TLGNTTSSVILTNYMDTQYYGEIGIGTPPQTFKVVFDTGSSNVWVPSSKCSRLYTACVYHKLFDASDSSSYKHNGTELTLRYSTGTVSGFLSQDIITVGGITVTQMFGEVTEMPALPFMLAEFDGVVGMGFIEQAIGRVTPIFDNIISQGVLKEDVFSFYYNRDSQSLGGQIVLGGSDPQHYEGNFHYINLIKTGVWQIQMKGVSVGSSTLLCEDGCLALVDTGASYISGSTSSIEKLMEALGAKKRLFDYVVKCNEGPTLPDISFHLGGKEYTLTSADYVFQESYSSKKLCTLAIHAMDIPPPTGPTWALGATFIRKFYTEFDRRNNRIGFALAR