4x4l A 1.85 BS01 3XG A 1 S121 M175 W178 Y297 G458 F466 S113 M167 W170 Y289 G450 F458 N170 K193 E269 C303 E400 E477 N162 K185 E261 C295 E392 E469 1.2.1.19,1.2.1.28,1.2.1.3,1.2.1.36 0000166,0001523,0001758,0004029,0005096,0005497,0005515,0005737,0005829,0006081,0006629,0009449,0016491,0016620,0018479,0019145,0030392,0030424,0036438,0042572,0042995,0045202,0051287,0070062,0106373,0110095,0120163 ic50=4.6uM IC50=20nM, EC50=3040nM, Ki=230nM P00352 25634381 603 LPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLSDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS