4x21 A 1.95 BS01 3WH A 1 V78 A91 M146 M149 D150 A151 N152 Q155 L206 V33 A46 M101 M104 D105 A106 N107 Q110 L161 D189 K191 N194 D207 T226 D144 K146 N149 D162 T167 2.7.11.24 0004672,0004707,0005524,0006468 Kd=36nM -logKd/Ki=7.44, Kd=36nM P53779 26505827 501 NQFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIDEREHTIEEWKELIYKEVMN 4x21 B 1.95 BS01 3WH B 1 S72 V78 A91 M146 M149 A151 N152 L206 S26 V32 A45 M100 M103 A105 N106 L160 D189 K191 N194 D207 T226 D143 K145 N148 D161 T167 2.7.11.24 0004672,0004707,0005524,0006468 Kd=36nM P53779 26505827 501 QFYSVEVGDSTFTVLKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPQIDEREHTIEEWKELIYKEVMN