4cnh A 1.9 BS01 3U9 A 1 L1122 A1148 M1199 N1254 L1256 G1269 L29 A42 M93 N148 L150 G163 D1249 A1251 R1253 N1254 D1270 D143 A145 R147 N148 D164 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Ki=4nM -logKd/Ki=8.40, Ki=4.0nM IC50=95nM, Ki=4.0nM Q9UM73 24819116 2402 PNYCFAGKTSSISDLKEVPRKNITLIRGLEVYEGQVSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIEY 4cnh B 1.9 BS01 3U9 A 1 I1399 E1400 I292 E293 D1249 A1251 R1253 N1254 D1270 D147 A149 R151 N152 D168 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Ki=4nM IC50=95nM, Ki=4.0nM Q9UM73 24819116 2402 NPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIE 4cnh B 1.9 BS02 3U9 B 1 L1122 G1123 V1130 A1148 L1196 M1199 G1202 N1254 L1256 G1269 D1270 L30 G31 V38 A49 L97 M100 G103 N152 L154 G167 D168 D1249 A1251 R1253 N1254 D1270 D147 A149 R151 N152 D168 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Ki=4nM IC50=95nM, Ki=4.0nM Q9UM73 24819116 2401 NPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIE 4cnh B 1.9 BS03 3U9 B 2 D1163 M1166 E1167 F1271 R1275 Y1278 D64 M67 E68 F169 R173 Y176 D1249 A1251 R1253 N1254 D1270 D147 A149 R151 N152 D168 2.7.10.1 0004672,0004713,0004714,0005524,0006468,0007169,0016020 Ki=4nM IC50=95nM, Ki=4.0nM Q9UM73 24819116 2402 NPNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSPLQVAVKTLPEVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQSLPRFILLELMAGGDLKSFLRETRPRPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGMARDIYRASYCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSKSNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVINTALPIE