3rdh A 2.39 BS01 3RD A 1 K120 I217 K123 I220 ? 0000122,0001525,0003016,0003723,0005515,0005615,0005634,0005654,0005737,0005829,0005925,0006468,0006605,0007165,0008039,0008104,0019901,0019904,0030324,0031625,0031647,0031982,0035148,0042149,0042470,0042802,0043066,0043067,0044325,0045296,0045824,0050815,0051683,0070062,0070371,0070372,0072562,0090128,0090168,0098686,0098978,0140297,0140311,1900181,1904262 -logKd/Ki=5.03, IC50=9.3uM IC50=9300nM P63104 21908710 246 GSHMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 3rdh B 2.39 BS01 3RD B 1 K120 G169 I217 K123 G172 I220 ? 0000122,0001525,0003016,0003723,0005515,0005615,0005634,0005654,0005737,0005829,0005925,0006468,0006605,0007165,0008039,0008104,0019901,0019904,0030324,0031625,0031647,0031982,0035148,0042149,0042470,0042802,0043066,0043067,0044325,0045296,0045824,0050815,0051683,0070062,0070371,0070372,0072562,0090128,0090168,0098686,0098978,0140297,0140311,1900181,1904262 IC50=9300nM P63104 21908710 246 GSHMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 3rdh C 2.39 BS01 3RD C 1 K49 K120 G169 K52 K123 G172 ? 0000122,0001525,0003016,0003723,0005515,0005615,0005634,0005654,0005737,0005829,0005925,0006468,0006605,0007165,0008039,0008104,0019901,0019904,0030324,0031625,0031647,0031982,0035148,0042149,0042470,0042802,0043066,0043067,0044325,0045296,0045824,0050815,0051683,0070062,0070371,0070372,0072562,0090128,0090168,0098686,0098978,0140297,0140311,1900181,1904262 IC50=9300nM P63104 21908710 246 GSHMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS 3rdh D 2.39 BS01 3RD D 1 K49 K120 G169 N173 K52 K123 G172 N176 ? 0000122,0001525,0003016,0003723,0005515,0005615,0005634,0005654,0005737,0005829,0005925,0006468,0006605,0007165,0008039,0008104,0019901,0019904,0030324,0031625,0031647,0031982,0035148,0042149,0042470,0042802,0043066,0043067,0044325,0045296,0045824,0050815,0051683,0070062,0070371,0070372,0072562,0090128,0090168,0098686,0098978,0140297,0140311,1900181,1904262 IC50=9300nM P63104 21908710 246 GSHMDKNELVQKAKLAEQAERYDDMAACMKSVTEQGAELSNEERNLLSVAYKNVVGARRSSWRVVSSIEQKTEGAEKKQQMAREYREKIETELRDICNDVLSLLEKFLIPNASQAESKVFYLKMKGDYYRYLAEVAAGDDKKGIVDQSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDEAIAELDTLSEESYKDSTLIMQLLRDNLTLWTS