3o0g B 1.95 BS01 3O0 B 1 I10 V18 A31 K33 C83 D84 Q85 L133 N144 I5 V8 A15 K17 C59 D60 Q61 L109 N120 N131 N144 C157 N270 V272 R274 I275 D288 N107 N120 C133 N246 V248 R250 I251 D264 2.7.11.1 0000226,0000307,0001764,0001963,0002039,0004672,0004674,0004693,0005176,0005515,0005524,0005634,0005654,0005737,0005829,0005874,0005886,0006338,0006468,0006886,0006915,0007160,0007268,0007399,0007409,0007416,0007519,0008017,0008045,0008306,0008542,0014044,0014069,0016020,0016079,0016241,0016301,0016310,0016477,0016533,0018105,0018107,0019233,0021537,0021549,0021695,0021697,0021766,0021819,0021954,0021987,0022038,0030027,0030036,0030054,0030175,0030182,0030334,0030424,0030425,0030426,0030517,0030549,0030900,0031175,0031397,0031594,0031914,0032801,0035249,0035418,0042220,0042981,0042995,0043005,0043025,0043113,0043125,0043204,0043525,0044024,0045202,0045786,0045861,0045892,0045956,0046826,0048148,0048156,0048167,0048488,0048489,0048511,0048675,0048709,0048813,0050321,0051301,0051402,0051649,0051726,0051879,0051966,0060078,0060079,0061001,0070509,0090314,0098793,0106310,1903076,1903421,1904646 Ki=0.6uM -logKd/Ki=6.22, Ki=0.6uM Q00535 16039528 293 KLEKIGTVFKAEIVALKRVRPSSALREICLLKELKHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLANFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD