6chi A 2.698 BS02 3NX A 1 A113 Y201 N202 R239 G297 D298 T306 A84 Y172 N173 R210 G259 D260 T268 T306 F435 C442 T268 F397 C404 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 IC50=120nM P05093 29792703 601 SLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQA 6chi B 2.698 BS02 3NX B 1 A113 Y201 N202 I205 R239 G297 D298 T306 V366 A84 Y172 N173 I176 R210 G261 D262 T270 V330 T306 F435 C442 T270 F399 C406 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 IC50=120nM P05093 29792703 601 SLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQA 6chi C 2.698 BS02 3NX C 1 A113 Y201 N202 I205 G297 D298 T306 V366 V482 A85 Y173 N174 I177 G268 D269 T277 V337 V453 T306 F435 C442 T277 F406 C413 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 IC50=120nM P05093 29792703 601 KSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDNGAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREAQAE 6chi D 2.698 BS02 3NX D 1 A113 Y201 N202 I205 I206 R239 G297 D298 A302 T306 A85 Y173 N174 I177 I178 R211 G262 D263 A267 T271 T306 F435 C442 T271 F400 C407 1.14.14.19,1.14.14.32 0004497,0004508,0005506,0005783,0005789,0006694,0006702,0006704,0007548,0008202,0008395,0016020,0016705,0016829,0019825,0020037,0030424,0042445,0042446,0042448,0043025,0046872 IC50=120nM P05093 29792703 601 KSLLSLPLVGSLPFLPRHGHMHNNFFKLQKKYGPIYSVRMGTKTTVIVGHHQLAKEVLIKKGKDFSGRPQMATLDIASNNRKGIAFADSGAHWQLHRRLAMATFALFKDGDQKLEKIICQEISTLCDMLATHNGQSIDISFPVFVAVTNVISLICFNTSYKNGDPELNVIQNYNEGIIDNLSKDSLVDLVPWLKIFPNKTLEKLKSHVKIRNDLLNKILENYKEKFRSDSITNMLDTLMQAKMNSDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLHNPQVKKKLYEEIDQNVGFSRTPTISDRNRLLLLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDDGQLPSLEGIPKVVFLIDSFKVKIKVRQAWREA