4rab A 2.264 BS01 3L3 A 1 D137 T138 G139 T141 K165 F186 V187 D193 D118 T119 G120 T122 K146 F167 V168 D174 E133 D134 D137 F186 R199 E114 D115 D118 F167 R180 2.4.2.8 0000166,0000287,0001913,0001975,0004422,0005515,0005737,0005829,0006164,0006166,0006178,0007625,0007626,0016757,0021756,0021895,0021954,0032263,0032264,0042417,0042802,0043103,0044209,0045964,0046038,0046040,0046083,0046100,0046651,0046872,0048813,0051289,0052657,0070062,0071542 Ki=0.04uM -logKd/Ki=7.40, Ki=0.04uM P00492 25494538 301 PGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKSDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYK 4rab B 2.264 BS01 3L3 B 1 I135 D137 T138 G139 T141 K165 F186 V187 D193 I121 D123 T124 G125 T127 K151 F170 V171 D177 E133 D134 D137 F186 R199 E119 D120 D123 F170 R183 2.4.2.8 0000166,0000287,0001913,0001975,0004422,0005515,0005737,0005829,0006164,0006166,0006178,0007625,0007626,0016757,0021756,0021895,0021954,0032263,0032264,0042417,0042802,0043103,0044209,0045964,0046038,0046040,0046083,0046100,0046651,0046872,0048813,0051289,0052657,0070062,0071542 Ki=0.04uM P00492 25494538 301 SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSPMTVDFIRLKSKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 4rab C 2.264 BS01 3L3 C 1 D137 T138 G139 K140 T141 K165 F186 V187 D193 D123 T124 G125 K126 T127 K151 F172 V173 D179 E133 D134 D137 F186 R199 E119 D120 D123 F172 R185 2.4.2.8 0000166,0000287,0001913,0001975,0004422,0005515,0005737,0005829,0006164,0006166,0006178,0007625,0007626,0016757,0021756,0021895,0021954,0032263,0032264,0042417,0042802,0043103,0044209,0045964,0046038,0046040,0046083,0046100,0046651,0046872,0048813,0051289,0052657,0070062,0071542 Ki=0.04uM -logKd/Ki=7.40, Ki=0.04uM P00492 25494538 301 PGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKIKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA 4rab D 2.264 BS01 3L3 D 1 D137 T138 G139 T141 K165 F186 V187 L192 D193 D122 T123 G124 T126 K150 F171 V172 L177 D178 E133 D134 D137 F186 R199 E118 D119 D122 F171 R184 2.4.2.8 0000166,0000287,0001913,0001975,0004422,0005515,0005737,0005829,0006164,0006166,0006178,0007625,0007626,0016757,0021756,0021895,0021954,0032263,0032264,0042417,0042802,0043103,0044209,0045964,0046038,0046040,0046083,0046100,0046651,0046872,0048813,0051289,0052657,0070062,0071542 Ki=0.04uM P00492 25494538 301 SPGVVISDDEPGYDLDLFCIPNHYAEDLERVFIPHGLIMDRTERLARDVMKEMGGHHIVALCVLKGGYKFFADLLDYIKALNRNSDRSIPMTVDFIRLKVIGGDDLSTLTGKNVLIVEDIIDTGKTMQTLLSLVRQYNPKMVKVASLLVKRTPRSVGYKPDFVGFEIPDKFVVGYALDYNEYFRDLNHVCVISETGKAKYKA