4w9x A 2.14 BS01 3JW A 1 A58 E59 G60 S63 A77 V109 M130 C133 Q137 E184 N185 L187 D198 A20 E21 G22 S25 A39 V71 M89 C92 Q96 E142 N143 L145 D156 D180 K182 N185 D198 N208 T226 D138 K140 N143 D156 N166 T184 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.40, Kd=39.8nM Q9NSY1 26853940 403 VGVRVFAVGRHQVTLEESLAEGGFSTVFLVRTHGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISWEVLILMEYCRAGQVVNQMNKKQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQVSYFAFKFAAADCPVSNINNSSIPSALPEPMT 6vn8 A 1.9 BS01 3JW A 1 L855 G856 K857 G858 V863 A880 M929 L932 R980 N981 L983 D994 L21 G22 K23 G24 V29 A46 M95 L98 R146 N147 L149 D160 D976 R980 N981 D994 D142 R146 N147 D160 2.7.10.2 0004672,0004713,0005524,0006468 IC50=5.7nM O60674 33570945 1201 LYFQGDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG 6vn8 B 1.9 BS01 3JW B 1 L855 G856 K857 G858 V863 A880 M929 E930 L932 R980 N981 L983 G993 D994 L13 G14 K15 G16 V21 A38 M87 E88 L90 R138 N139 L141 G151 D152 D976 R980 N981 D994 D134 R138 N139 D152 2.7.10.2 0004672,0004713,0005524,0006468 IC50=5.7nM O60674 33570945 1201 QFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMA 6wto A 1.74 BS01 3JW A 1 L855 G856 V863 A880 M929 L932 R980 L983 G993 D994 L13 G14 V21 A35 M78 L81 R129 L132 G142 D143 D976 R980 N981 D994 D125 R129 N130 D143 2.7.10.2 0004672,0004713,0005524,0006468 IC50=5.7nM O60674 34110416 1203 QFEERHLKFLQQLGKGNFGSVEMCRYDPLTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKSPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAGGS