3pce C 2.06 BS01 3HP O 1 G14 P15 G14 P15 Y79 V114 M122 H125 N127 Y79 V114 M122 H125 N127 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0042952,0051213 P00436 9254599 550 PIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF 3pce E 2.06 BS01 3HP Q 1 G14 P15 G14 P15 Y79 V114 M122 H125 N127 Y79 V114 M122 H125 N127 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0042952,0051213 P00436 9254599 550 PIELLPETPSQTAGPYVHIGLALEAAGNPTRDQEIWNRLAKPDAPGEHILLLGQVYDGNGHLVRDSFLEVWQADANGEYQDAYNLENAFNSFGRTATTFDAGEWTLHTVKPGVVNNAAGVPMAPHINISLFARGINIHLHTRLYFDDEAQANAKCPVLNLIEQPQRRETLIAKRCEVDGKTAYRFDIRIQGEGETVFFDF 3pce M 2.06 BS02 3HP M 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM -logKd/Ki=2.00, Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce N 2.06 BS02 3HP N 1 Y447 W449 R457 H462 I491 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce O 2.06 BS02 3HP O 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce P 2.06 BS02 3HP P 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM -logKd/Ki=2.00, Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce Q 2.06 BS02 3HP Q 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 3pce R 2.06 BS02 3HP R 1 Y408 Y447 W449 R457 H462 I491 Y105 Y144 W146 R154 H159 I188 Y408 Y447 R457 H460 H462 Y105 Y144 R154 H157 H159 1.13.11.3 0003824,0005506,0008199,0009056,0016702,0018578,0019619,0042952,0046872,0051213 Ki=10mM P00437 9254599 550 PAQDNSRFVIRDRNWHPKALTPDYKTSIARSPRQALVSIPQSISETTGPNFSHLGFGAHDHDLLLNFGLPIGERIIVAGRVVDQYGKPVPNTLVEMWQANAGGRYRHKNDRYLAPLDPNFGGVGRCLTDSDGYYSFRTIKPGPYPWRNGPNDWRPAHIHFGISGPSIATKLITQLYFEGDPLIPMCPIVKSIANPEAVQQLIAKLDMNNANPMDCLAYRFDIVLRGQRKTHFE 5izz A 1.6 BS01 3HP A 1 W90 Y95 R169 P171 V191 E211 I212 F239 W66 Y71 R145 P147 V167 E187 I188 F215 0055085 401 EVVLKFHSFPPMPANSNAKFVKPWSEKVLAESNGEIKVEIYPAMQLGGKPPQLVDQVRDGVVDIVWTVAGYTPGRFPHLEAFELPFMPASAEATSQALQEYVDTVAASDLKDYKVLAVFCHAPGKIHTKEKVIASAADLNGMKMRGPTRVITKMLEGLGATPVGMPVPAVAGALSKGVIDGMVVPWEIMPSFKLHELTAAHTTVSGSRGLYTTPFLFLMNKAKYESLSDEHKKVIDNNAGLALAKLAGQLWDGFEVPARKLALDAGGTIHSLSGGPLAEMKAAGEGLEADWIKSANDRGLDGAMLVKTAKDLISKYDK 5rtg A 1.01 BS01 3HP A 1 A129 G130 V155 F156 D157 L160 A127 G128 V153 F154 D155 L158 2.1.1.56,2.1.1.57,2.7.7.48,2.7.7.50,3.1.13.-,3.4.19.12,3.4.22.-,3.4.22.69,3.6.4.12,3.6.4.13,4.6.1.- P0DTD1 33853786 201 VNSFSGYLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESDDYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLAPLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFL