4cae A 1.46 BS02 3F3 A 1 V96 E97 D98 F105 Y107 Y211 Y315 S319 Y334 N365 A366 L367 L388 L409 L410 V70 E71 D72 F79 Y81 Y185 Y289 S293 Y308 N339 A340 L341 L362 L383 L384 N161 F162 L163 T197 L410 N135 F136 L137 T171 L384 2.3.1.97 0004379,0005737,0006499,0016746,0018008,0046872 Ki=18nM -logKd/Ki=7.74, Ki=18nM A5K1A2 24641010 1414 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 4cae B 1.46 BS02 3F3 B 1 V96 E97 F103 F105 Y107 Y211 Y315 S319 Y334 S335 N365 A366 L367 L388 L409 L410 V70 E71 F77 F79 Y81 Y185 Y289 S293 Y308 S309 N339 A340 L341 L362 L383 L384 N161 F162 L163 T197 L410 N135 F136 L137 T171 L384 2.3.1.97 0004379,0005737,0006499,0016746,0018008,0046872 Ki=18nM A5K1A2 24641010 1414 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFSSLNSRLTMSRAIKLYRVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL 4cae C 1.46 BS02 3F3 C 1 V96 E97 D98 F103 F105 Y107 Y211 Y315 S319 Y334 N365 A366 L367 L409 L410 V70 E71 D72 F77 F79 Y81 Y185 Y272 S276 Y291 N322 A323 L324 L366 L367 N161 F162 L163 T197 L410 N135 F136 L137 T171 L367 2.3.1.97 0004379,0005737,0006499,0016746,0018008,0046872 Ki=18nM A5K1A2 24641010 1413 DYKFWYTQPVPKINDEFNESVNEPFISDNKVEDVRKDEYKLPPGYSWYVCDVKDEKDRSEIYTLLTDNYVEDDDNIFRFNYSAEFLLWALTSPNYLKTWHIGVKYDASNKLIGFISAIPTDICIHKRTIKMAEVNFLCVHKTLRSKRLAPVLIKEITRRINLENIWQAIYTAGVYLPKPVSDARYYHRSINVKKLIEIGFVEDTLNIKNMRLMKKKDVEGVHKLLGSYLEQFNLYAVFTKEEIAHWFLPIENVIYTYVNEENGKIKDMISFYSLPSQILGNDKYSTLNAAYSFYNVTTTATFKQLMQDAILLAKRNNFDVFNALEVMQNKSVFEDLKFGEGDGSLKYYLYNWKCASFAPAHVGIVLL