4aq3 A 2.4 BS01 398 A 1 F63 Y67 D70 M74 E95 L96 F36 Y40 D43 M47 E68 L69 ? 0042981 ic50=37nM -logKd/Ki=7.43, IC50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 A 2.4 BS02 398 E 1 Q58 L160 Y161 G162 Q31 L133 Y134 G135 ? 0042981 ic50=37nM -logKd/Ki=7.43, IC50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 B 2.4 BS01 398 B 1 F63 Y67 D70 F71 M74 E95 L96 Y161 F36 Y40 D43 F44 M47 E68 L69 Y134 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 B 2.4 BS02 398 D 1 Q58 L160 Y161 G162 Q31 L133 Y134 G135 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 C 2.4 BS01 398 C 1 F63 Y67 D70 F71 M74 E95 L96 Y161 F36 Y40 D43 F44 M47 E68 L69 Y134 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 D 2.4 BS01 398 B 1 Q58 Y161 G162 Q33 Y136 G137 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDSEVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 D 2.4 BS02 398 D 1 F63 Y67 D70 F71 M74 E95 L96 F38 Y42 D45 F46 M49 E70 L71 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDSEVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 E 2.4 BS01 398 A 1 Q58 L160 Y161 G162 Q31 L133 Y134 G135 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 DNREIVMKYIHYKLSQRGYEWDAVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 E 2.4 BS02 398 E 1 F63 Y67 D70 E95 Y161 F36 Y40 D43 E68 Y134 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 DNREIVMKYIHYKLSQRGYEWDAVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG 4aq3 F 2.4 BS01 398 F 1 F63 Y67 D70 F71 M74 V92 E95 L96 A108 F38 Y42 D45 F46 M49 V67 E70 L71 A83 ? 0042981 ic50=37nM P10415,Q07817 22608961 1163 YDNREIVMKYIHYKLSQRGYEWDAEVVHLALRQAGDDFSRRYRGDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG