4qq5 A 2.203 BS01 37O A 1 L478 E480 C482 F483 E525 I539 L555 C557 A558 A559 G561 L624 D635 F636 L32 E34 C36 F37 E74 I88 L104 C106 A107 A108 G110 L160 D171 F172 D617 A619 R621 N622 D635 D153 A155 R157 N158 D171 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=6.32, IC50=482nM P22455 25317566 801 QDPLLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVILECAAKGNLREFLRARRPPGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLALPVKWMAPEALFDEVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 4qqc A 2.4 BS01 37O A 1 L473 E475 C477 F478 I534 V550 C552 A553 L619 D630 L31 E33 C35 F36 I87 V103 C105 A106 L159 D170 D612 A614 R616 N617 D630 D152 A154 R156 N157 D170 2.7.10.1 0004672,0004713,0005524,0006468 -logKd/Ki=7.34, IC50=45.3nM P22455 25349422 801 DPLLAGLVSLDLPLDPLWEFPRDRLVLGKPLGEGCFGQVVRAEAFGMDQASTVAVKMLKDNASDKDLADLVSEMEVMKLIGRHKNIINLLGVCTQEGPLYVIVECAAKGNLREFLRARRPPGPLSFPVLVSCAYQVARGMQYLESRKCIHRDLAARNVLVTEDNVMKIADFGLLPVKWMAPEALFDEVYTHQSDVWSFGILLWEIFTLGGSPYPGIPVEELFSLLREGHRMDRPPHCPPELYGLMRECWHAAPSQRPTFKQLVEALDKVLLAV 7d57 A 2.104 BS01 37O A 1 L273 G276 C277 A293 K295 I336 T338 Y340 M341 G344 A390 N391 L393 D404 F405 L16 G19 C20 A36 K38 I79 T81 Y83 M84 G87 A133 N134 L136 D147 F148 2.7.10.2 0004672,0004713,0005524,0006468 P00523 601 DAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL 7d57 B 2.104 BS01 37O B 1 L273 V281 A293 E310 M314 Y340 M341 G344 S345 D348 L393 A403 D404 F405 L17 V21 A33 E44 M48 Y74 M75 G78 S79 D82 L127 A137 D138 F139 2.7.10.2 0004672,0004713,0005524,0006468 P00523 601 KDAWEIPRESLRLEVKLGQEVWMGTWNGTTRVAIKTLPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKGEMGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGRLIFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTSTEPQYQPGENL