4twc A 1.7 BS01 37J A 1 A36 Y56 L85 G86 P87 D91 L92 L135 L293 A35 Y55 L84 G85 P86 D90 L91 L134 L291 D128 K130 D127 K129 2.7.11.1,2.7.11.26 0004672,0005524,0006468 -logKd/Ki=7.40, IC50=0.040uM IC50=22nM P48730 22331384 1007 ELRVGNRYRLGNKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF 4twc B 1.7 BS01 37J B 1 A36 Y56 L85 G86 P87 D91 L135 A36 Y56 L85 G86 P87 D91 L135 D128 K130 D128 K130 2.7.11.1,2.7.11.26 0004672,0005524,0006468 IC50=22nM P48730 22331384 1008 MELRVGNRYRLGNKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKARQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKF