4tpt A 2.6 BS01 35H A 1 K360 I363 M380 V388 L403 L442 H449 A468 D469 F470 L472 R474 K31 I34 M51 V59 L74 L113 H120 A139 D140 F141 L143 R145 D451 N453 H455 N456 D469 N509 D122 N124 H126 N127 D140 N157 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.04, IC50=92nM IC50=92nM P53671 25589930 701 DLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVKKRYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIPLPAELEELDHTVSMQYG 4tpt B 2.6 BS01 35H B 1 K360 L362 I363 M380 V388 T405 H449 A468 D469 F470 L472 R474 K31 L33 I34 M51 V59 T76 H120 A139 D140 F141 L143 R145 D451 N453 H455 N456 D469 N509 D122 N124 H126 N127 D140 N154 2.7.11.1 0004672,0005524,0006468 -logKd/Ki=7.04, IC50=92nM IC50=92nM P53671 25589930 701 DLIHGEVLGKGFFGQAIKVTHKATGKVMVMKELIRCDEETQKTFLTEVKVMRSLDHPNVLKFIGVLYKDKKLNLLTEYIEGGTLKDFLRSMDPFPWQQKVRFAKGIASGMAYLHSMCIIHRDLNSHNCLIKLDKTVVVADFGLSRLIVYTVVGNPYWMAPEMLNGKSYDETVDIFSFGIVLCEIIGQVYADPDCLPRTLDFGLNVKLFWEKFVPTDCPPAFFPLAAICCRLEPESRPAFSKLEDSFEALSLYLGELGIPLPAELEELDHTVSMQYGL