1p4r A 2.55 BS02 354 A 1 Q449 S450 R451 I452 P543 F544 D546 N547 S565 A566 Q446 S447 R448 I449 P540 F541 D543 N544 S562 A563 K266 H267 N431 H592 K263 H264 N428 H589 2.1.2.3,3.5.4.10 0003360,0003824,0003937,0004643,0005737,0005829,0005886,0006139,0006164,0006177,0006189,0016020,0016740,0016787,0021549,0021987,0031100,0042803,0044208,0045296,0046452,0046654,0070062,0097294,0098761 -logKd/Ki=8.10, Ki=8nM P31939 14966129 1801 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 1p4r A 2.55 BS05 354 B 1 K266 M312 F315 N489 K263 M309 F312 N486 K266 H267 N431 H592 K263 H264 N428 H589 2.1.2.3,3.5.4.10 0003360,0003824,0003937,0004643,0005737,0005829,0005886,0006139,0006164,0006177,0006189,0016020,0016740,0016787,0021549,0021987,0031100,0042803,0044208,0045296,0046452,0046654,0070062,0097294,0098761 -logKd/Ki=8.10, Ki=8nM P31939 14966129 1802 GQLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 1p4r B 2.55 BS02 354 A 1 K266 M312 F315 G316 N489 K262 M308 F311 G312 N485 K266 H267 N431 H592 K262 H263 N427 H588 2.1.2.3,3.5.4.10 0003360,0003824,0003937,0004643,0005737,0005829,0005886,0006139,0006164,0006177,0006189,0016020,0016740,0016787,0021549,0021987,0031100,0042803,0044208,0045296,0046452,0046654,0070062,0097294,0098761 -logKd/Ki=8.10, Ki=8nM P31939 14966129 1801 QLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH 1p4r B 2.55 BS04 354 B 1 Q449 S450 R451 I452 P543 F544 D546 N547 S565 A566 Q445 S446 R447 I448 P539 F540 D542 N543 S561 A562 K266 H267 N431 H592 K262 H263 N427 H588 2.1.2.3,3.5.4.10 0003360,0003824,0003937,0004643,0005737,0005829,0005886,0006139,0006164,0006177,0006189,0016020,0016740,0016787,0021549,0021987,0031100,0042803,0044208,0045296,0046452,0046654,0070062,0097294,0098761 -logKd/Ki=8.10, Ki=8nM P31939 14966129 1802 QLALFSVSDKTGLVEFARNLTALGLNLVASGGTAKALRDAGLAVRDVSELTGFPEMLGGRVKTLHPAVHAGILARNIPEDNADMARLDFNLIRVVACNLYPFVKTVASPGVTVEEAVEQIDIGGVTLLRAAAKNHARVTVVCEPEDYVVVSTEMQSSESKDTSLETRRQLALKAFTHTAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLQPKLPITVLNGAPGFINLCDALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKIISREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKPDENEVRTLFGLHLSQKRNNGVVDKSLFSNVVTKNKDLPESALRDLIVATIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPQVLSMKFKTGVKRAEISNAIDQYVTGTIGEDEDLIKWKALFEEVPELLTEAEKKEWVEKLTEVSISSDAFFPFRDNVDRAKRSGVAYIAAPSGSAADKVVIEACDELGIILAHTNLRLFHH