3ey4 A 3.0 BS02 352 A 1 T124 S125 S170 L171 A172 Y177 Y183 T100 S101 S146 L147 A148 Y153 Y159 S170 Y183 K187 S146 Y159 K163 1.1.1.146,1.1.1.201 0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196 Ki=35nM, IC50=34nM P28845 601 EEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYSTS 3ey4 B 3.0 BS02 352 B 1 S125 L126 S170 L171 A172 Y183 G216 S99 L100 S144 L145 A146 Y157 G190 S170 Y183 K187 S144 Y157 K161 1.1.1.146,1.1.1.201 0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196 Ki=35nM, IC50=34nM P28845 603 FRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYS 3ey4 C 3.0 BS02 352 C 1 S125 L126 L171 A172 Y177 Y183 M233 S100 L101 L146 A147 Y152 Y158 M208 S170 Y183 K187 S145 Y158 K162 1.1.1.146,1.1.1.201 0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196 Ki=35nM, IC50=34nM P28845 602 EFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYS 3ey4 D 3.0 BS02 352 D 1 T124 S125 L126 S170 L171 A172 Y177 V180 Y183 T100 S101 L102 S146 L147 A148 Y153 V156 Y159 S170 Y183 K187 S146 Y159 K163 1.1.1.146,1.1.1.201 0005496,0005783,0005789,0006706,0008202,0016020,0016491,0030324,0042803,0043231,0047022,0050661,0070524,0102196 Ki=35nM, IC50=34nM P28845 604 EEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPSRKILEFLYSTSYN