3f7z A 2.4 BS01 34O A 1 F67 A83 K85 D133 Y134 V135 L188 C199 D200 F34 A50 K52 D97 Y98 V99 L152 C163 D164 D181 K183 N186 D200 S219 D145 K147 N150 D164 S183 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=65nM -logKd/Ki=7.19, IC50=65nM IC50=65nM P49841 19200745 3000 LSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSGEEVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR 3f7z B 2.4 BS01 34O B 1 A83 K85 V110 L132 Y134 V135 L188 D200 A50 K52 V77 L93 Y95 V96 L149 D161 D181 K183 N186 D200 S219 D142 K144 N147 D161 S180 2.7.11.1,2.7.11.26 0004672,0005524,0006468 ic50=65nM IC50=65nM P49841 19200745 3000 LSKVTTVVATPGQGPDRPQEVSYTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNRELQIMRKLDHCNIVRLRYFFYSSVYLNLVLDYVPETVYRVARHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQLVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFFDELRDPNVKLPNGRDTPALFNFTTQELSSNPPLATILIPPHAR