2pjt A 2.8 BS06 347 A 1 L159 L160 A161 H197 E198 H201 H207 L214 P217 Y219 L81 L82 A83 H119 E120 H123 H129 L136 P139 Y141 H197 E198 H201 H207 H119 E120 H123 H129 3.4.24.- 0004222,0006508,0008237,0008270,0031012 -logKd/Ki=6.07, IC50=860nM IC50=860nM P45452 17606376 401 YNVFPRTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP 2pjt B 2.8 BS05 347 B 1 L160 A161 L193 V194 H197 E198 H201 H207 L214 P217 Y219 L81 A82 L114 V115 H118 E119 H122 H128 L135 P138 Y140 H197 E198 H201 H207 H118 E119 H122 H128 3.4.24.- 0004222,0006508,0008237,0008270,0031012 IC50=860nM P45452 17606376 401 YNVFPTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTGKSHFMLPDDDVQGIQSLYGP 2pjt C 2.8 BS05 347 C 1 Y151 L160 A161 H197 E198 H201 H207 L214 P217 Y219 Y71 L80 A81 H117 E118 H121 H127 L134 P137 Y139 H197 E198 H201 H207 H117 E118 H121 H127 3.4.24.- 0004222,0006508,0008237,0008270,0031012 IC50=860nM P45452 17606376 401 YNVFTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTFMLPDDDVQGIQSLYGP 2pjt D 2.8 BS05 347 D 1 L159 L160 A161 H197 E198 H201 H207 P217 I218 T220 L80 L81 A82 H118 E119 H122 H128 P138 I139 T141 H197 E198 H201 H207 H118 E119 H122 H128 3.4.24.- 0004222,0006508,0008237,0008270,0031012 IC50=860nM P45452 17606376 401 YNVFPTLKWSKMNLTYRIVNYTPDMTHSEVEKAFKKAFKVWSDVTPLNFTRLHDGIADIMISFGIKEHGDFYPFDGPSGLLAHAFPPGPNYGGDAHFDDDETWTSSSKGYNLFLVAAHEFGHSLGLDHSKDPGALMFPIYTYTHFMLPDDDVQGIQSLYGP