2oji A 2.6 BS01 33A A 1 G30 V37 K52 Q103 M106 L154 D165 G18 V25 K40 Q91 M94 L142 D153 D147 K149 S151 N152 D165 T188 D135 K137 S139 N140 D153 T176 2.7.11.24 0000165,0001784,0003677,0004672,0004674,0004707,0005515,0005524,0005576,0005634,0005654,0005737,0005739,0005769,0005770,0005788,0005794,0005813,0005819,0005829,0005856,0005886,0005901,0005925,0006357,0006468,0006915,0006935,0006974,0007165,0007166,0007268,0007507,0007611,0008286,0008353,0009887,0010759,0010800,0014032,0014044,0016020,0016301,0016310,0018105,0018107,0019858,0019902,0030278,0030521,0030641,0030878,0031143,0031647,0031663,0032206,0032496,0032872,0033554,0033598,0034198,0035094,0035556,0035578,0038127,0038133,0042473,0042552,0042802,0043330,0043401,0045202,0045542,0045596,0048009,0048538,0050847,0050852,0050853,0051403,0051493,0060020,0060291,0060324,0060425,0060440,0060716,0061308,0070161,0070371,0070849,0071356,0072584,0072686,0090170,0106310,0120041,1904813,2000641 -logKd/Ki=7.07, Ki=86nM Ki=85nM P28482 17300186 360 RGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNVNKVRVAIKKISPFEHQTYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRIEVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGY 2ok1 A 2.4 BS01 33A A 1 P69 I70 A74 V78 A91 K93 M146 E147 M149 D150 L206 P24 I25 A27 V31 A44 K46 M99 E100 M102 D103 L159 D189 K191 N194 D207 T226 D142 K144 N147 D160 T166 2.7.11.24 0004672,0004707,0005524,0006468 Ki=0.55uM -logKd/Ki=6.26, Ki=0.55uM Ki=550nM P53779 17300186 1 NQFYSVEVGDSTFTVLKRYQNLKPIGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNHKNIISLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHLHSAGIIHRDLKPSNIVVKSDCTLKILDFGLAVTRYYRAPEVILGMGYKENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVENRPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYINVWYDPAEVEAPPPDEREHTIEEWKELIYKEVMN