4q1b A 2.15 BS01 2Y0 A 1 E53 V55 L82 M85 Y86 Q97 D133 F137 N140 S144 Y204 E34 V36 L51 M54 Y55 Q66 D102 F106 N109 S113 Y173 E53 R128 E34 R97 2.7.1.113,2.7.1.74,2.7.1.76 0004136,0004137,0004138,0005515,0005524,0005634,0005654,0005737,0005739,0005829,0006139,0006220,0008144,0009224,0016301,0016310,0019136,0042803,0043771,0106383,1901135,1901293 Ki=1.9nM -logKd/Ki=8.72, Ki=1.9nM IC50=12nM, Ki=1.9nM P27707 25341194 301 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFGQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL 4q1b B 2.15 BS01 2Y0 B 1 E53 V55 M85 Y86 F96 Q97 D133 F137 E34 V36 M54 Y55 F65 Q66 D102 F106 E53 R128 E34 R97 2.7.1.113,2.7.1.74,2.7.1.76 0004136,0004137,0004138,0005515,0005524,0005634,0005654,0005737,0005739,0005829,0006139,0006220,0008144,0009224,0016301,0016310,0019136,0042803,0043771,0106383,1901135,1901293 Ki=1.9nM IC50=12nM, Ki=1.9nM P27707 25341194 301 RIKKISIEGNIAAGKSTFVNILKQLSEDWEVVPEPVARWSTMEQKNGGNVLQMMYEKPERWSFTFQTYACLSRIRAQLASLNGKLKDAEKPVLFFERSVYSDRYIFASNLYESESMNETEWTIYQDWHDWMNNQFQSLELDGIIYLQATPETCLHRIYLRGRNEEQGIPLEYLEKLHYKHESWLLHRTLKTNFDYLQEVPILTLDVNEDFKDKYESLVEKVKEFLSTL