4puk A 1.49 BS02 2WU A 1 D102 Y106 D156 C158 G229 L231 A232 M260 G261 D93 Y97 D144 C146 G217 L219 A220 M248 G249 D102 D280 C318 C320 C323 H349 D93 D268 C306 C308 C311 H337 2.4.2.29 0002099,0005737,0005829,0006400,0008033,0008479,0008616,0016757,0016763,0046872,0101030 Kd=52.4nM -logKd/Ki=7.28, Kd=52.4nM P28720 24955548 405 DRPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHSRHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4pul A 1.654 BS02 2WU A 1 Y106 D156 C158 G229 L231 A232 M260 G261 Y96 D140 C142 G213 L215 A216 M244 G245 N102 D280 C318 C320 C323 H349 N92 D264 C302 C304 C307 H333 2.4.2.29 0002099,0005737,0005829,0006400,0008033,0008479,0008616,0016757,0016763,0046872,0101030 Kd=146.1nM -logKd/Ki=6.84, Kd=146.1nM P28720 24955548 403 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTNSGGYQVMSLSSLTKQSEEGVTFKSHMLSPERSIEIQHLLGSDIVMAFDECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA 4pum A 1.93 BS02 2WU A 1 D102 Y106 N156 C158 G229 A232 M260 G261 D92 Y96 N143 C145 G216 A219 M247 G248 D102 D280 C318 C320 C323 H349 D92 D267 C305 C307 C310 H336 2.4.2.29 0002099,0005737,0005829,0006400,0008033,0008479,0008616,0016757,0016763,0046872,0101030 Kd=188.1nM -logKd/Ki=6.73, Kd=188.1nM P28720 24955548 404 RPRFSFSIAAREGKARTGTIEMKRGVIRTPAFMPVGTAATVKALKPETVRATGADIILGNTYHLMLRPGAERIAKLGGLHSFMGWDRPILTDSGGYQVMSLSSLTKQSEEGVTFKSHSRHMLSPERSIEIQHLLGSDIVMAFNECTPYPATPSRAASSMERSMRWAKRSRDAFDSRKEQAENAALFGIQQGSVFENLRQQSADALAEIGFDGYAVGGLAVGEGQDEMFRVLDFSVPMLPDDKPHYLMGVGKPDDIVGAVERGIDMFDCVLPTRSGRNGQAFTWDGPINIRNARFSEDLKPLDSECHCAVCQKWSRAYIHHLIRAGEILGAMLMTEHNIAFYQQLMQKIRDSISEGRFSQFAQDFRARYFA