4otg A 2.6 BS01 2V9 A 1 L627 G628 F632 V635 A648 Y703 S704 G707 L753 L17 G18 F22 V25 A38 Y93 S94 G97 L143 D746 K748 D750 N751 D764 T784 D136 K138 D140 N141 D154 T174 2.7.11.13 0004672,0004674,0005524,0006468 -logKd/Ki=7.59, IC50=26nM Q16512 25111382 1001 LRKSPLTLEDFKFLAVLGRGHFGKVLLSEFRPSGELFAIKALKKGDIVARDEVESLMCEKRILAAVTSAGHPFLVNLFGCFQTPEHVCFVMEYSAGGDLMLHIHSDVFSEPRAIFYSACVVLGLQFLHEHKIVYRDLKLDNLLLDTEGYVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTDTSYTRAVDWWGLGVLLYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSAEAIGIMRRLLRRNPERRLGSSERDAEDVKKQPFFRTLGWEALLARRLPPPFVPTLFTGEAPTLSPPRDARPLTAAEQAAFLDFDFVAG 5wnj A 2.55 BS01 2V9 A 1 V28 V36 A49 K51 L82 M96 E97 Y98 M99 G102 A147 L150 D161 V19 V25 A38 K40 L71 M85 E86 Y87 M88 G91 A136 L139 D150 N143 A147 N148 D161 N132 A136 N137 D150 2.7.11.1 0004672,0005524,0006468 Q9ERK0 29706531 401 ALGLLRTFDAGEFAGWEKVGSFGQVYKVRHVHWKTWLAIKCSPSLHVDDRERMELLEEAKKMEMAKFRYILPVYGICQEPVGLVMEYMETGSLEKLLASEPLPWDLRFRIVHETAVGMNFLHCMSPPLLHLNLKPANILLDAHYHVKISDFGLAKCFGTIAYLPPERIREKSRLFDTKHDVYSFAIVIWGVLTQKKPFADEKNILHIMMKVVKGHRPELPPICRPRPRACASLIGLMQRCWHADPQVRPTFQEITSETEDLCEK 8bpw A 1.8 BS01 2V9 A 1 L855 G856 K857 G858 V863 A880 K882 M929 Y931 L932 G935 R980 L983 D994 L23 G24 K25 G26 V31 A48 K50 M97 Y99 L100 G103 R148 L151 D162 2.7.10.2 0004672,0004713,0005524,0006468 O60674 38843875 1201 NLYFQSMDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG 8bpw B 1.8 BS01 2V9 B 1 L855 G858 V863 A880 K882 M929 Y931 L932 G935 R980 L983 D994 L23 G26 V31 A48 K50 M97 Y99 L100 G103 R148 L151 D162 2.7.10.2 0004672,0004713,0005524,0006468 O60674 38843875 1201 NLYFQSMDPTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIEILKSLQHDNIVKYKGVCYSAGRRNLKLIMEYLPYGSLRDYLQKHKERIDHIKLLQYTSQICKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQDKEYYKVKEPGESPIFWYAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIELLKNNGRLPRPDGCPDEIYMIMTECWNNNVNQRPSFRDLALRVDQIRDNMAG