3kc1 A 2.25 BS01 2T6 A 1 V17 G21 A24 G26 T27 G28 E29 L30 K112 Y113 M177 V9 G13 A16 G18 T19 G20 E21 L22 K96 Y97 M161 D74 E97 E98 D118 L120 D121 E280 D58 E81 E82 D102 L104 D105 E264 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 ic50=1nM -logKd/Ki=9.00, IC50=1nM IC50=1nM P09467 20045638 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 3kc1 B 2.25 BS01 2T6 B 1 V17 G21 A24 G26 T27 G28 E29 L30 K112 Y113 R140 M177 V9 G13 A16 G18 T19 G20 E21 L22 K95 Y96 R123 M160 D74 E97 E98 D118 L120 D121 E280 D57 E80 E81 D101 L103 D104 E263 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 ic50=1nM IC50=1nM P09467 20045638 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 3kc1 C 2.25 BS01 2T6 C 1 V17 G21 A24 G26 T27 G28 E29 L30 K112 Y113 M177 V9 G13 A16 G18 T19 G20 E21 L22 K95 Y96 M160 D74 E97 E98 D118 L120 D121 E280 D57 E80 E81 D101 L103 D104 E263 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 ic50=1nM -logKd/Ki=9.00, IC50=1nM IC50=1nM P09467 20045638 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS 3kc1 D 2.25 BS01 2T6 D 1 V17 G21 A24 G26 T27 G28 E29 L30 K112 Y113 R140 M177 V9 G13 A16 G18 T19 G20 E21 L22 K94 Y95 R122 M159 D74 E97 E98 D118 L120 D121 E280 D56 E79 E80 D100 L102 D103 E262 3.1.3.11 0000122,0005515,0005615,0005634,0005737,0005829,0005975,0005986,0006000,0006002,0006094,0006111,0016208,0016311,0016787,0016791,0030308,0030388,0031667,0032869,0042132,0042578,0042802,0045820,0046580,0046872,0048029,0061629,0070062,0071286,0071320,0071466,0071475,0071477,0097403,1904628 ic50=1nM IC50=1nM P09467 20045638 401 DVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHS