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BioLiP
Download all results in tab-seperated text for 13 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2e2r:A (1.6) BS01 2OH ? N/A P62508 17761695 MOAD: Kd=5.5nM
    PDBbind: -logKd/Ki=8.26, Kd=5.5nM
    BindingDB: IC50=13.1nM
    2 2p7g:A (2.1) BS01 2OH ? N/A P62508 17964775 MOAD: Kd=0.297uM
    PDBbind: -logKd/Ki=6.53, Kd=0.297uM
    BindingDB: IC50=13.1nM
    3 3uu7:A (2.196) BS02 2OH ? N/A P03372 22927406 BindingDB: IC50=>10000nM, EC50=>10000nM
    4 3uu7:B (2.196) BS02 2OH ? N/A P03372 22927406 BindingDB: IC50=>10000nM, EC50=>10000nM
    5 5it1:A (2.1) BS02 2OH 1.14.14.1 GO:0004497 ... Q70AS3 27231902
    6 5it1:B (2.1) BS02 2OH 1.14.14.1 GO:0004497 ... Q70AS3 27231902
    7 5it1:C (2.1) BS02 2OH 1.14.14.1 GO:0004497 ... Q70AS3 27231902
    8 5it1:D (2.1) BS02 2OH 1.14.14.1 GO:0004497 ... Q70AS3 27231902
    9 6i63:A (2.229) BS01 2OH ? N/A P62508 31127318 MOAD: Kd=98nM
    BindingDB: IC50=13.1nM
    10 6lit:A (2.0) BS02 2OH ? N/A O95718 32795533
    11 6lit:B (2.0) BS02 2OH ? N/A O95718 32795533
    12 9f7w:A (1.25) BS02 2OH N/A N/A P37231 38927044
    13 9f7w:A (1.25) BS03 2OH N/A N/A P37231 38927044
    Reference:
  • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023).
  • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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