4i4z A 2.0 BS01 2NE A 1 H29 K30 R31 S75 G76 G77 D78 Q79 Y87 V98 G123 T145 V149 S151 H29 K30 R31 S75 G76 G77 D78 Q79 Y87 V98 G123 T145 V149 S151 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z A 2.0 BS03 2NE F 1 F260 K263 F260 K263 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z B 2.0 BS01 2NE B 1 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 G123 T145 V149 S151 K29 R30 A32 S74 G75 G76 D77 Q78 Y86 G122 T144 V148 S150 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G76 R81 Y86 R94 L98 G122 V125 G145 S150 D152 G153 A239 Y247 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 DWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z B 2.0 BS03 2NE D 1 F260 K263 F259 K262 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G76 R81 Y86 R94 L98 G122 V125 G145 S150 D152 G153 A239 Y247 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 DWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z C 2.0 BS01 2NE C 1 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 I121 G123 T145 V149 S151 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 I121 G123 T145 V149 S151 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z C 2.0 BS03 2NE E 1 F260 K263 F260 K263 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z D 2.0 BS01 2NE B 1 F260 K263 F260 K263 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z D 2.0 BS02 2NE D 1 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z E 2.0 BS01 2NE C 1 F260 K263 F260 K263 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z E 2.0 BS02 2NE E 1 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 S151 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 S151 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z F 2.0 BS01 2NE A 1 F260 K263 F260 K263 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z F 2.0 BS02 2NE F 1 K30 R31 A33 S75 G76 G77 D78 Q79 G123 T145 V149 S151 F152 K30 R31 A33 S75 G76 G77 D78 Q79 G123 T145 V149 S151 F152 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z G 2.0 BS01 2NE G 1 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 I121 G123 T145 V149 H29 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 I121 G123 T145 V149 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z H 2.0 BS01 2NE H 1 R31 S75 G77 D78 Q79 Y87 Y119 G123 T145 S151 F152 R31 S75 G77 D78 Q79 Y87 Y119 G123 T145 S151 F152 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4i4z I 2.0 BS01 2NE I 1 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 S151 K30 R31 A33 S75 G76 G77 D78 Q79 Y87 V98 Y119 G123 T145 V149 S151 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 G77 R82 Y87 R95 L99 G123 V126 G146 S151 D153 G154 A240 Y248 4.1.3.36 0003824,0005829,0008935,0009234,0016829,0042372 P73495 23658663 301 MDWHIAKHYDDILYYKAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYYMTEEGSEGKQAFLEKRPPDFSQYPWLP 4qii A 1.64 BS01 2NE A 1 V57 R58 A60 F61 S103 G104 G105 D106 Q107 I136 W157 G160 G161 T184 D185 V188 S190 V43 R44 A46 F47 S89 G90 G91 D92 Q93 I122 W143 G146 G147 T170 D171 V174 S176 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G91 R96 Y101 R116 H121 G147 S150 D171 S176 D178 G179 A265 Y273 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 LSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii A 1.64 BS02 2NE F 1 Y287 F299 K302 Y273 F285 K288 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G91 R96 Y101 R116 H121 G147 S150 D171 S176 D178 G179 A265 Y273 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 LSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii B 1.64 BS01 2NE B 1 V57 R58 A60 K95 S103 G105 D106 Q107 Y115 W157 G160 G161 T184 D185 V188 S190 V44 R45 A47 K82 S90 G92 D93 Q94 Y102 W144 G147 G148 T171 D172 V175 S177 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii B 1.64 BS02 2NE E 1 Y287 F299 K302 Y274 F286 K289 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii C 1.64 BS01 2NE C 1 V57 R58 A60 S103 G104 G105 D106 Q107 W157 G161 T184 D185 S190 V44 R45 A47 S90 G91 G92 D93 Q94 W144 G148 T171 D172 S177 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii C 1.64 BS02 2NE D 1 Y287 F299 K302 Y274 F286 K289 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii D 1.64 BS01 2NE C 1 F299 K302 F284 K287 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G90 R95 Y100 R115 H120 G146 S149 D170 S175 D177 G178 A264 Y272 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 SDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii D 1.64 BS02 2NE D 1 V57 R58 A60 S103 G104 G105 D106 Q107 Y115 W157 A159 G161 T184 D185 S190 V42 R43 A45 S88 G89 G90 D91 Q92 Y100 W142 A144 G146 T169 D170 S175 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G90 R95 Y100 R115 H120 G146 S149 D170 S175 D177 G178 A264 Y272 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 SDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii E 1.64 BS01 2NE B 1 F299 K302 F283 K286 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii E 1.64 BS02 2NE E 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 G161 T184 D185 V188 S190 V41 R42 A44 K79 S87 G88 G89 D90 Q91 Y99 W141 G145 T168 D169 V172 S174 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii F 1.64 BS01 2NE A 1 F299 K302 F283 K286 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii F 1.64 BS02 2NE F 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 T184 D185 V188 S190 V41 R42 A44 K79 S87 G88 G89 D90 Q91 Y99 W141 T168 D169 V172 S174 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii G 1.64 BS01 2NE G 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 G161 T184 D185 S190 V44 R45 A47 K82 S90 G91 G92 D93 Q94 Y102 W144 G148 T171 D172 S177 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii G 1.64 BS02 2NE L 1 Y287 F299 K302 Y274 F286 K289 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii H 1.64 BS01 2NE H 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 G161 T184 S190 V44 R45 A47 K82 S90 G91 G92 D93 Q94 Y102 W144 G148 T171 S177 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii H 1.64 BS02 2NE K 1 Y287 F299 K302 Y274 F286 K289 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii I 1.64 BS01 2NE I 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 T184 D185 V188 S190 V44 R45 A47 K82 S90 G91 G92 D93 Q94 Y102 W144 T171 D172 V175 S177 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii I 1.64 BS02 2NE J 1 F299 K302 F286 K289 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G92 R97 Y102 R117 H122 G148 S151 D172 S177 D179 G180 A266 Y274 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 ALSDNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii J 1.64 BS01 2NE I 1 Y287 F299 K302 Y270 F282 K285 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G88 R93 Y98 R113 H118 G144 S147 D168 S173 D175 G176 A262 Y270 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 NPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii J 1.64 BS02 2NE J 1 V57 R58 A60 S103 G104 G105 D106 Q107 Y115 W157 A159 G161 T184 D185 V188 S190 V40 R41 A43 S86 G87 G88 D89 Q90 Y98 W140 A142 G144 T167 D168 V171 S173 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G88 R93 Y98 R113 H118 G144 S147 D168 S173 D175 G176 A262 Y270 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 NPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii K 1.64 BS01 2NE H 1 Y287 F299 K302 Y271 F283 K286 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii K 1.64 BS02 2NE K 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 G161 T184 D185 S190 V41 R42 A44 K79 S87 G88 G89 D90 Q91 Y99 W141 G145 T168 D169 S174 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii L 1.64 BS01 2NE G 1 F299 K302 F283 K286 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF 4qii L 1.64 BS02 2NE L 1 V57 R58 A60 K95 S103 G104 G105 D106 Q107 Y115 W157 G161 T184 D185 V188 S190 V41 R42 A44 K79 S87 G88 G89 D90 Q91 Y99 W141 G145 T168 D169 V172 S174 G105 R110 Y115 R130 H135 G161 S164 D185 S190 D192 G193 A279 Y287 G89 R94 Y99 R114 H119 G145 S148 D169 S174 D176 G177 A263 Y271 4.1.3.36 0005886,0008935,0009234,0016829,0034214 P9WNP5 25372686 401 DNPFDAKAWRLVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQAQRMLKFAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPRYF