1dgj A 2.8 BS03 2MO A 1 G424 R535 G698 E869 G424 R535 G698 E869 V391 F427 R503 Y507 R535 E869 M870 V391 F427 R503 Y507 R535 E869 M870 1.2.-.- 0005506,0016491,0046872,0051536,0051537 Q9REC4 10704312 910 METKTLIVNGMARRLLVSPNDLLVDVLRSQLQLTSVKVGCGKGQCGACTVILDGKVVRACIIKMSRVAENASVTTLEGIGAPDCLHPLQHAWIQHGAAQCGFCTPGFIVSAKALLDENVAPSREDVRDWFQKHHNICRCTGYKPLVDAVMDAAAILRGEKTVEEISFKMPADGRIWGSSIPRPSAVAKVTGLAEFGADAALRMPENTLHLALAQAKVSHALIKGIDTSEAEKMPGVYKVLTHKDVKGKNRITGLITFPTNKGDGWERPILNDSKIFQYGDALAIVCADSEANARAAAEKVKFDLELLPEYMSAPEAMAPDAIEIHPGTPNVYYDQLEEKGEDTVPFFNDPANVVAEGSYYTQRQPHLPIEPDVGYGYINEQGQVVIHSKSVAIHLHALMIAPGLGLEFPKDLVLVQNTTGGTFGYKFSPTMEALVGVAVMATGRPCHLRYNYEQQQNYTGKRSPFWTTMRYAADRQGKILAMETDWSVDHGPYSEFGDLLTLRGAQYIGAGYGIANIRGTGRTVATNHCWGAAFRGYGAPESEFPSEVLMDELAEKLGMDPFELRALNCYREGDTTSSGQIPEVMSLPEMFDKMRPYYEESKKRVKERSTAEIKRGVGVALGVYGAGLDGPDTSEAWVELNDDGSVTLGNSWEDHGQGADAGSLGTAHEALRPLGITPENIHLVMNDTSKTPNSGPAGGSRSQVVTGNAIRVACEMLIEGMRKPGGGFFTPAEMKAEGRPMRYDGKWTAPAKDCDAKGQGSPFACYMYGLFLTEVAVEVATGKATVEKMVCVADIGKICNKLVVDGQIYGGLAQGVGLALSEDYEDLKKHSTMGGAGIPSIKMIPDDIEIVYVETPRKDGPFGASGVGEMPLTAPHAAIINGIYNACGARVRHLPARPEKVLEAMP 1dms A 1.88 BS03 2MO A 1 Y114 W116 Y146 S147 Y112 W114 Y144 S145 M41 Y114 W116 D145 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M39 Y112 W114 D143 S145 T146 V151 I152 W320 S355 Y356 H357 Y358 1.7.2.3,1.8.5.3 0009033,0009055,0009061,0016491,0030151,0030288,0042597,0043546,0046872,0050626 Q52675 8890912 784 LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPTPMLEGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPQGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGADHVTPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLMGETDSTPKTAEWASDISGVPAETIKELARLFKSKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSSSGPALSGITDGGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFIVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGKEFTEGKDEMGWIKSFYDDAAKQGKAGGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEAGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e5v A 2.4 BS03 2MO A 1 W116 S147 W114 S145 M41 Y114 W116 D145 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M39 Y112 W114 D143 S145 T146 V151 I152 W320 S355 Y356 H357 Y358 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVQMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e5v C 2.4 BS03 2MO C 1 W116 S147 W114 S145 M41 W116 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M39 W114 S145 T146 V151 I152 W320 S355 Y356 H357 Y358 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVQMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e60 A 2.0 BS03 2MO A 1 Y114 W116 D145 Y146 S147 Y111 W113 D142 Y143 S144 M41 Y114 W116 D145 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M38 Y111 W113 D142 S144 T145 V150 I151 W319 S354 Y355 H356 Y357 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 ANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGAATKGPEWLAASGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e60 C 2.0 BS03 2MO C 1 Y114 W116 Y146 S147 Y112 W114 Y144 S145 M41 W116 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M39 W114 S145 T146 V151 I152 W320 S355 Y356 H357 Y358 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGAASGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e61 A 1.9 BS03 2MO A 1 W116 S147 W113 S144 M41 Y114 W116 D145 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M38 Y111 W113 D142 S144 T145 V150 I151 W319 S354 Y355 H356 Y357 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 ANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1e61 C 1.9 BS03 2MO C 1 W116 S147 W114 S145 M41 W116 S147 T148 V153 I154 W322 S357 Y358 H359 Y360 M39 W114 S145 T146 V151 I152 W320 S355 Y356 H357 Y358 1.7.2.3,1.8.5.3 0016491,0043546 Q52675 10985771 803 LANGTVMSGSHWGVFTATVENGRATAFTPWEKDPHPSPMLAGVLDSIYSPTRIKYPMVRREFLEKGVNADRSTRGNGDFVRVSWDQALDLVAAEVKRVEETYGPEGVFGGSYGWKSPGRLHNCTTLLRRMLTLAGGYVNGAGDYSTGAAQVIMPHVVGTLEVYEQQTAWPVLAENTEVMVFWAADPIKTSQIGWVIPEHGAYPGLEALKAKGTKVIVIDPVRTKTVEFFGAEHITPKPQTDVAIMLGMAHTLVAEDLYDKDFIANYTSGFDKFLPYLDGETDSTPKTAEWAEGISGVPAETIKELARLFESKRTMLAAGWSMQRMHHGEQAHWMLVTLASMLGQIGLPGGGFGLSYHYSGGGTPSTSGPALAGITDGGGASVIPVARVVDMLENPGAEFDFNGTRSKFPDVKMAYWVGGNPFVHHQDRNRMVKAWEKLETFVVHDFQWTPTARHADIVLPATTSYERNDIETIGDYSNTGILAMKKIVEPLYEARSDYDIFAAVAERLGKGAEFTEGKDEMGWIKSFYDDAAKQGKAAGVEMPAFDAFWAEGIVEFPVTDGADFVRYASFREDPLLNPLGTPTGLIEIYSKNIEKMGYDDCPAHPTWMEPLERLDGPGAKYPLHIAASHPFNRLHSQLNGTVLREGYAVQGHEPCLMHPDDAAARGIADGDVVRVHNDRGQILTGVKVTDAVMKGVIQIYEGGWYDPSDVTEPGTLDKYGDVNVLSADIGTSKLAQGNCGQTVLAEVEKYTGPAVTLTGFVAPKAAE 1tmo A 2.5 BS03 2MO A 1 W118 S149 W114 S145 T116 W118 D147 S149 T150 G363 Y366 T112 W114 D143 S145 T146 G359 Y362 1.7.2.3 0016491,0030151,0042597,0043546,0050626 O87948 9813128 801 NEDEWLTTGSHFGAFKMKRKNGVIAEVKPFDLDKYPTDMINGIRGMVYNPSRVRYPMVRLDFLLKGHKSNTHQRGDFRFVRVTWDKALTLFKHSLDEVQTQYGPSGLHAGQTGWRATGQLHSSTSHMQRAVGMHGNYVKKIGDYSTGAGQTILPYVLGSTEVYAQGTSWPLILEHSDTIVLWSNDPYKNLQVGWNAETHESFAYLAQLKEKVKQGKIRVISIDPVVTKTQAYLGCEQLYVNPQTDVTLMLAIAHEMISKKLYDDKFIQGYSLGFEEFVPYVMGTKDGVAKTPEWAAPICGVEAHVIRDLAKTLVKGRTQFMMGWCIQRQQHGEQPYWMAAVLATMIGQIGLPGGGISYGHHYSSIGVPSSGAAAPGAFPRNLDENQKPLFDSSDFKGASSTIPVARWIDAILEPGKTIDANGSKVVYPDIKMMIFSGNNPWNHHQDRNRMKQAFHKLECVVTVDVNWTATCRFSDIVLPACTTYERNDIDVYGAYANRGILAMQKMVEPLFDSLSDFEIFTRFAAVLGKEKEYTRNMGEMEWLETLYNECKAANAGKFEMPDFATFWKQGYVHFGDGEVWTRHADFRNDPEINPLGTPSGLIEIFSRKIDQFGYDDCKGHPTWMEKTERSHGGPGSDKHPIWLQSCHPDKRLHSQMCESREYRETYAVNGREPVYISPVDAKARGIKDGDIVRVFNDRGQLLAGAVVSDNFPKGIVRIHEGAWYGPVGKDGSTEGGAEVGALCSYGDPNTLTLDIGTSKLAQACSAYTCLVEFEKYQGKVPKVSSFDGPIEVEI 2xts A 1.33 BS01 2MO A 1 R114 C160 A161 N261 Y286 R73 C119 A120 N220 Y245 R114 C160 K285 Y286 R73 C119 K244 Y245 1.8.2.1 0006790,0008482,0016491,0020037,0030151,0043546,0046872 P72178 21147779 501 GTPDPLITEIQPWASEFGEAVDAHPYGLPIHFESHVKRQYVEWLTESPVSSINFTPIHALEGTITPQGCAFERHHSGAIELSKQDYRLMINGLVEKPLVFTFEDLLRFPRTTTTAFCECAANGGMEWGGAQLEGCQYTQGMIHNMEYVGVPLSVLLAEAGVKPEGKWLYAEGADASSNGRSFPMEKVMDDVMLAFFANGEALRKEHGYPARLVVPGWEGNMWVKWVRRLGIYDKAVESREETSKYTDLMPDGRARKWTWVMDAKSVITSPSPQVPIRHGKGPLVISGLAWSGNGRITRVDVSLDGGKNWTTARITGQALPKALTRFHLDIDWDGSEMLLQSRAVDETGYVQPTKDALRAIRGRNNVYHNNGIQTWWVKADGEVENVEIA 2xts C 1.33 BS01 2MO C 1 R114 C160 A161 N261 Y286 R73 C119 A120 N220 Y245 R114 C160 K285 Y286 R73 C119 K244 Y245 1.8.2.1 0006790,0008482,0016491,0020037,0030151,0043546,0046872 P72178 21147779 501 GTPDPLITEIQPWASEFGEAVDAHPYGLPIHFESHVKRQYVEWLTESPVSSINFTPIHALEGTITPQGCAFERHHSGAIELSKQDYRLMINGLVEKPLVFTFEDLLRFPRTTTTAFCECAANGGMEWGGAQLEGCQYTQGMIHNMEYVGVPLSVLLAEAGVKPEGKWLYAEGADASSNGRSFPMEKVMDDVMLAFFANGEALRKEHGYPARLVVPGWEGNMWVKWVRRLGIYDKAVESREETSKYTDLMPDGRARKWTWVMDAKSVITSPSPQVPIRHGKGPLVISGLAWSGNGRITRVDVSLDGGKNWTTARITGQALPKALTRFHLDIDWDGSEMLLQSRAVDETGYVQPTKDALRAIRGRNNVYHNNGIQTWWVKADGEVENVEIA