4nj9 H 1.95 BS01 2M9 H 1 G97 Y98 G99 R100A G100B G101 Y102 G103 R105 G106 ? -logKd/Ki=6.97, Kd=108nM Q9D8L4 25756188 501 EVQLQQSGPELVKPGTSVKMSCKASGYTFTDYYMHWVKQSHGKSLEWIGYIYPNNGGNGYNQKFKGKATLTVDKSSSTAYMELRSLTSEDSAVYYCARRGGYGSRGYFDVWGTGTTVTVSSAKTTAPSVYPLAPVGSSVTLGCLVKGYFPEPVTLTWNSGSLSSGVHTFPALLQSGLYTLSSSVTVTSNTWPSQTITCNVAHPASSTKVDKKIEPRG 4nj9 L 1.95 BS04 2M9 H 1 Y28 I30 F32 R50 Y32 I34 F36 R54 ? -logKd/Ki=6.97, Kd=108nM Q52L95 25756188 501 DIVLTQSPASLAVSLGQRATISCRASESVDSYGISFMHWYQQKPGQPPKLLIYRASNLESGIPARFSGSGSRTDFTLTIIPVEADDVATYYCQQSNEDPRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATSPIVKSFNRNE 4nja H 2.204 BS01 2M9 H 1 G97 Y98 G99 I100 R100A G100B G101 Y102 G103 I104 R105 G106 ? -logKd/Ki=6.22, Kd=600nM A0A0F7R1P3 25756188 501 EVQLQQSGPELVKPGASVKMSCKASGYTFTDYYMHWVKQSHGKSLEWIGYIYPNNGGNGYNQKFKGKATLTVDKSSSTAYMELRSLTSDDSAVYYCARRGGYGIRGYFDVWGTGTTVTVSSAKTTPPSVYPLAPGCGDTTGSSVTSGCLVKGYFPEPVTVTWNSGSLSSSVHTFPALLQSGLYTMSSSVTVPSSTWPSQTVTCSVAHPASSTTVDKKLEPS 4nja L 2.204 BS02 2M9 H 1 Y28 N30 F32 R50 Y32 N34 F36 R54 ? 0002250,0005615,0006955,0019814 -logKd/Ki=6.22, Kd=600nM P01660,Q52L95 25756188 501 DIVLTQSPASLAVSLGQRATISCRASESVDSYGNSFMHWYQQKPGQPPKLLIYRASNLESGIPARFSGSGSRTDFTLTINPVEADDVATYYCQQSNEDPRTFGGGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNE 6m87 A 2.609 BS01 2M9 B 1 Y32 H34 W91 N94 Y31 H33 W90 N93 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6m87 B 2.609 BS01 2M9 B 1 N33 G95 G96 G97 F98 R99 G100A N32 G98 G99 G100 F101 R102 G104 31243995 301 FQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 B 2.609 BS02 2M9 J 1 S157 L158 S159 P183 S160 L161 S162 P186 31243995 301 FQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 C 2.609 BS01 2M9 D 1 Y32 W91 Y31 W90 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6m87 D 2.609 BS01 2M9 D 1 G95 G97 F98 R99 G99 G101 F102 R103 31243995 301 PFQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 E 2.609 BS01 2M9 E 1 Y32 H34 W91 N94 Y31 H33 W90 N93 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6m87 F 2.609 BS01 2M9 E 1 N58 G95 G96 G97 F98 G100A N58 G98 G99 G100 F101 G104 31243995 301 FQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 G 2.609 BS01 2M9 G 1 Y32 H34 W91 N94 Y31 H33 W90 N93 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQVLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6m87 H 2.609 BS01 2M9 B 1 S157 L158 P183 S160 L161 P186 31243995 301 FQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 H 2.609 BS02 2M9 G 1 N58 G95 G96 G97 F98 R99 N58 G98 G99 G100 F101 R102 31243995 301 FQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 I 2.609 BS01 2M9 J 1 Y32 W91 N94 Y31 W90 N93 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQLNSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRN 6m87 J 2.609 BS01 2M9 J 1 N58 G95 G96 G97 F98 R99 G100A N59 G99 G100 G101 F102 R103 G105 31243995 301 PFQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN 6m87 K 2.609 BS01 2M9 K 1 Y32 H34 W91 Y31 H33 W90 31243995 301 PLVLTQSPAIMSASPGEKVTMTCSASSSVSYVHWYQQKSGTSPKRWIYDTSKLASGVPARFSGSGSGTSYSLTISSMEAEDAATYYCHQWRTNPPTFGAGTKLEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQVLNSWTDQDSKDSTYSMSSTLTLTKDERHNSYTCEATHKTSTSPIVKSFNRN 6m87 L 2.609 BS01 2M9 K 1 N33 G95 G97 F98 R99 G100A N33 G99 G101 F102 R103 G105 31243995 301 PFQLLESGPELVKPGASVKISCKASGYSFTDYNMNWVKQSNGKSLEWIGVINPNSGTTNYNQKFKDKATLTVDQSSSTAYMQLNSLTSEDSAVYYCARGGGFRRGFDSWGQGTTVTVSSAKTTPPSVYPLAPVAQTNSVTLGCLVKGYFPEPVTVTWNSGSLSSGVHTFPAVLQSDLYTLSSSVTVPSSTWPSQSVTCNVAHPASSTAVDKKIEPN