2za5 A 2.3 BS01 2FF A 1 Y177 D203 S204 C205 Q206 V227 W229 G230 E231 G232 R238 Y162 D188 S189 C190 Q191 V212 W214 G215 E216 G217 R223 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=3.7nM -logKd/Ki=8.43, Ki=3.7nM P20231 18272363 4 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 2za5 B 2.3 BS01 2FF B 1 Y177 I189 D203 S204 C205 Q206 W229 G230 E231 G232 Y162 I174 D188 S189 C190 Q191 W214 G215 E216 G217 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=3.7nM P20231 18272363 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 2za5 C 2.3 BS01 2FF C 1 Y177 D203 S204 C205 Q206 W229 G230 E231 G232 R238 Y162 D188 S189 C190 Q191 W214 G215 E216 G217 R223 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=3.7nM -logKd/Ki=8.43, Ki=3.7nM P20231 18272363 2 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP 2za5 D 2.3 BS01 2FF D 1 Y177 D203 S204 C205 Q206 W229 G230 E231 G232 R238 Y162 D188 S189 C190 Q191 W214 G215 E216 G217 R223 H59 D106 Q206 G207 D208 S209 G210 H44 D91 Q191 G192 D193 S194 G195 3.4.21.59 0004252,0005515,0005576,0005615,0006508,0008236,0062023 Ki=3.7nM P20231 18272363 3 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQFYTAQIGADIALLELEEPVKVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVP