4mqp A 1.83 BS01 2B1 A 1 W64 W65 G124 S125 Y157 H158 E220 A226 D254 I256 K283 Y407 W57 W58 G117 S118 Y150 H151 E213 A219 D247 I249 K276 Y400 Y25 Y157 E220 D254 A257 K283 Y407 Y18 Y150 E213 D247 A250 K276 Y400 2.6.1.62 0004015,0005737,0008483,0009102,0030170 -logKd/Ki=4.98, Ki=10.4uM P9WQ81 24482078 501 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVGS 4mqp B 1.83 BS01 2B1 A 1 P317 T318 P310 T311 Y25 Y157 E220 D254 A257 K283 Y407 Y18 Y150 E213 D247 A250 K276 Y400 2.6.1.62 0004015,0005737,0008483,0009102,0030170 -logKd/Ki=4.98, Ki=10.4uM P9WQ81 24482078 501 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG 4mqp B 1.83 BS02 2B1 B 1 W65 G124 S125 Y157 H158 E220 A226 D254 I256 K283 F402 Y407 W58 G117 S118 Y150 H151 E213 A219 D247 I249 K276 F395 Y400 Y25 Y157 E220 D254 A257 K283 Y407 Y18 Y150 E213 D247 A250 K276 Y400 2.6.1.62 0004015,0005737,0008483,0009102,0030170 -logKd/Ki=4.98, Ki=10.4uM P9WQ81 24482078 501 LTPEQIIAVDGAHLWHPYSSIGREAVSPVVAVAAHGAWLTLIRDGQPIEVLDAMSSWWTAIHGHGHPALDQALTTQLRVMNHVMFGGLTHEPAARLAKLLVDITPAGLDTVFFSDSGSVSVEVAAKMALQYWRGRGLPGKRRLMTWRGGYHGDTFLAMSICDPHGGMHSLWTDVLAAQVFAPQVPRDYDPAYSAAFEAQLAQHAGELAAVVVEPVVQGAGGMRFHDPRYLHDLRDICRRYEVLLIFDEIATGFGRTGALFAADHAGVSPDIMCVGKALTGGYLSLAATLCTADVAHTISAGAAGALMHGPTFMANPLACAVSVASVELLLGQDWRTRITELAAGLTAGLDTARALPAVTDVRVCGAIGVIECDRPVDLAVATPAALDRGVWLRPFRNLVYAMPPYICTPAEITQITSAMVEVARLVG