2ofv A 2.0 BS01 242 A 1 V259 A271 V272 K273 E288 L291 M292 I314 T316 Y318 M319 A381 D382 F383 V29 A41 V42 K43 E51 L54 M55 I77 T79 Y81 M82 A144 D145 F146 D364 R366 A368 N369 D382 D127 R129 A131 N132 D145 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.2nM -logKd/Ki=9.70, IC50=0.2nM IC50=0.2nM P06239 16970394 503 KPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLAIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFF 2ofv B 2.0 BS01 242 B 1 V259 A271 K273 E288 L291 M292 L300 I314 T316 Y318 M319 L371 I380 A381 D382 F383 V28 A40 K42 E52 L55 M56 L64 I78 T80 Y82 M83 L135 I144 A145 D146 F147 D364 R366 A368 N369 D382 D128 R130 A132 N133 D146 2.7.10.2 0004672,0004713,0005524,0006468 ic50=0.2nM IC50=0.2nM P06239 16970394 503 PWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTINKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPIQNLEGYRMVRPDNCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFT